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Bilateral

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Also Known As

Affecting both sides, two-sided, on both sides, ambilateral, involving paired structures, symmetrically distributed

Definition

Bilateral refers to a condition, structure, or process that affects both sides of the body or paired organs simultaneously.1 The term is derived from Latin, where “bi” means two, and “lateral” means to the side.2 In medical contexts, bilateral describes conditions or procedures involving both of a pair of organs or structures, such as both kidneys, both lungs, both testicles, or both sides of the body.3 Many anatomical structures in the human body are bilateral, as our bodies are frequently mirror images on the left and right sides.2 Bilateral conditions can be congenital (present at birth) or acquired through disease processes, and they may require different treatment approaches compared to unilateral (one-sided) conditions.4

Clinical Context

In clinical practice, the term bilateral is used to describe conditions, findings, or procedures that involve both sides of paired structures.1 For example, bilateral kidney stones would indicate stones present in both kidneys, while bilateral orchidectomy refers to the surgical removal of both testicles.3

In urology specifically, bilateral conditions are particularly significant as they often indicate systemic disease processes rather than localized pathology.2 For instance, bilateral hydronephrosis (enlargement of the parts of the kidney that collect urine on both sides) may suggest a lower urinary tract obstruction affecting the entire system rather than a unilateral obstruction like a single kidney stone.4

When evaluating patients, clinicians must distinguish between unilateral and bilateral presentations, as this distinction often affects diagnostic workup, treatment planning, and prognosis.1 For example, bilateral testicular pain may suggest systemic conditions like mumps orchitis or autoimmune disorders, while unilateral pain might indicate torsion or local trauma.3

Treatment approaches for bilateral conditions often require more comprehensive management strategies compared to unilateral conditions, as they may affect overall organ system function more significantly.2 In some cases, such as bilateral kidney disease, the impact on overall renal function may be more severe, potentially leading to systemic complications that require more aggressive intervention.4

Scientific Citation

[1] Camarillo ND, Jiménez-Silva R, Sheehan FT. Using Bilateral Data in Controls and Patients with Bilateral and Unilateral Pathology Requires Increased Scrutiny. J Biomech. 2023 Oct 30;162:111855. DOI: 10.1016/j.jbiomech.2023.111855

[2] Whitlock J. How the Word Bilateral Is Used in Medicine. Verywell Health. Updated July 4, 2024. https://www.verywellhealth.com/bilateral-defined-3157050

[3] Kansas City Urology Care. Glossary of Urology Terms. 2023. https://www.kcuc.com/resources/glossary-of-urology-terms/

[4] Strupp M, Kim JS, Murofushi T, et al. Bilateral vestibulopathy: Diagnostic criteria Consensus document of the Classification Committee of the Bárány Society. J Vestib Res. 2017;27(4):177-189. DOI: 10.3233/VES-170619