{"id":12762,"date":"2025-07-24T10:33:48","date_gmt":"2025-07-24T14:33:48","guid":{"rendered":"https:\/\/www.rigicon.com\/glossary-term\/estrogen\/"},"modified":"2026-10-06T18:19:32","modified_gmt":"2026-10-06T22:19:32","slug":"estrogenio","status":"publish","type":"glossary-term","link":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/","title":{"rendered":"Estrog\u00eanio"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","glossary-category":[137],"glossary-product":[108,107],"class_list":["post-12762","glossary-term","type-glossary-term","status-publish","hentry","glossary-category-hormone-therapy","glossary-product-conticlassic-aus","glossary-product-contireflex-enhanced-aus"],"acf":{"gt-definition":"<p>\n        O estrog\u00eanio \u00e9 um grupo de horm\u00f4nios sexuais femininos que pode ser usado em certos tratamentos urol\u00f3gicos, particularmente para tratar condi\u00e7\u00f5es relacionadas ao trato urin\u00e1rio inferior nas mulheres.<span class=\"citation\">\u00b9<\/span> Quimicamente, os estrog\u00eanios pertencem \u00e0 fam\u00edlia de compostos org\u00e2nicos conhecidos como esteroides, com uma estrutura central composta por 18 \u00e1tomos de carbono (estradiol: C18H24O2) organizados em quatro an\u00e9is fundidos.<span class=\"citation\">\u00b2<\/span> Os principais tipos incluem estrona (E1), estradiol (E2), estriol (E3) e estetrol (E4), sendo o estradiol a forma circulante predominante durante os anos reprodutivos.<span class=\"citation\">\u00b2<\/span> Os estrog\u00eanios s\u00e3o sintetizados principalmente nos ov\u00e1rios, mas tamb\u00e9m nas gl\u00e2ndulas suprarrenais e no tecido adiposo.<span class=\"citation\">\u00b2<\/span>\n    <\/p>\n    <p>\n        Em contextos urol\u00f3gicos, o estrog\u00eanio atua ligando-se a receptores de estrog\u00eanio (ERs) espec\u00edficos presentes nos tecidos do trato urin\u00e1rio inferior, incluindo a vagina, a uretra e o tr\u00edgono vesical.<span class=\"citation\">\u00b3<\/span> Esses receptores, quando ativados, iniciam processos de transcri\u00e7\u00e3o e eventos de sinaliza\u00e7\u00e3o que influenciam a estrutura e a fun\u00e7\u00e3o dos tecidos.<span class=\"citation\">\u00b2<\/span> A queda dos n\u00edveis de estrog\u00eanio ap\u00f3s a menopausa leva a altera\u00e7\u00f5es atr\u00f3ficas significativas nos tecidos urogenitais, que podem resultar em diversos sintomas e condi\u00e7\u00f5es urol\u00f3gicas.<span class=\"citation\">\u2074<\/span> A terapia estrog\u00eanica local \u00e9 particularmente ben\u00e9fica no tratamento dessas condi\u00e7\u00f5es, pois normaliza a acidez dos tecidos, aumenta a espessura e a lubrifica\u00e7\u00e3o e restaura o microbioma vaginal, reduzindo o risco de infec\u00e7\u00e3o do trato urin\u00e1rio.<span class=\"citation\">\u2075<\/span>\n    <\/p>","gt-synonyms":"Estrog\u00eanio, Horm\u00f4nio sexual feminino, Estradiol, Estriol, Estrona, Estretrol, Horm\u00f4nio feminizante","gt-citation":"[1] Kim DK, Chancellor MB. Is Estrogen for Urinary Incontinence Good or Bad? Rev Urol. 2006;8(2):91-92. PMID: 17021635. PMCID: PMC1578535\n\n[2] Fuentes N, Silveyra P. Estrogen receptor signaling mechanisms. Adv Protein Chem Struct Biol. 2019;116:135-170. DOI: 10.1016\/bs.apcsb.2019.01.001\n\n[3] Robinson D, Cardozo L. The role of estrogens in female lower urinary tract dysfunction. Urology. 2003;62(4 Suppl 1):45-51. DOI: 10.1016\/S0090-4295(03)00676-9\n\n[4] Rosenblum N. Update in Female Hormonal Therapy: What the Urologist Should Know. Rev Urol. 2020;22(4):182-185. PMCID: PMC8058921\n\n[5] Escobar C, Rosenblum N. Vaginal Estrogen\u2014What a Urologist Should Know. Urology. 2021;151:37-43. DOI: 10.1016\/j.urology.2020.05.034. PMID: 32504683","gt-clinical-context":"<p>\n        O estrog\u00eanio desempenha um papel significativo na manuten\u00e7\u00e3o da sa\u00fade e da fun\u00e7\u00e3o do trato urin\u00e1rio inferior nas mulheres.<span class=\"citation\">\u00b3<\/span> Na urologia cl\u00ednica, a terapia com estrog\u00eanio \u00e9 usada principalmente para tratar condi\u00e7\u00f5es decorrentes da defici\u00eancia de estrog\u00eanio, particularmente em mulheres na p\u00f3s-menopausa.<span class=\"citation\">\u2074<\/span> O trato urin\u00e1rio inferior e os tecidos vaginais s\u00e3o ricos em receptores de estrog\u00eanio, e a deple\u00e7\u00e3o de estrog\u00eanio associada \u00e0 menopausa leva a altera\u00e7\u00f5es nesses tecidos, incluindo comprometimento da lubrifica\u00e7\u00e3o, da elasticidade, do pH e do fluxo sangu\u00edneo.<span class=\"citation\">\u2074<\/span>\n    <\/p>\n    <p>\n        A terapia estrog\u00eanica local \u00e9 usada para tratar as altera\u00e7\u00f5es atr\u00f3ficas urogenitais da pele que ocorrem na vagina, na uretra e na vulva quando os ov\u00e1rios deixam de produzir estrog\u00eanio ap\u00f3s a menopausa.<span class=\"citation\">\u2075<\/span> Mulheres com atrofia vaginal frequentemente apresentam sintomas como secura vaginal, sensibilidade e dor durante a rela\u00e7\u00e3o sexual.<span class=\"citation\">\u2075<\/span> As altera\u00e7\u00f5es da pele que ocorrem na uretra e no tr\u00edgono vesical podem resultar em sintomas urin\u00e1rios, incluindo frequ\u00eancia, urg\u00eancia, dis\u00faria (mic\u00e7\u00e3o dolorosa) e maior suscetibilidade a infec\u00e7\u00f5es do trato urin\u00e1rio (ITUs).<span class=\"citation\">\u2075<\/span>\n    <\/p>\n    <p>\n        A diretriz de 2019 da American Urological Association para ITUs recorrentes n\u00e3o complicadas em mulheres recomenda a terapia com estrog\u00eanio vaginal para mulheres na peri e p\u00f3s-menopausa, a fim de reduzir o risco de ITUs recorrentes.<span class=\"citation\">\u2074<\/span> V\u00e1rios ensaios cl\u00ednicos randomizados controlados mostraram que diversas formas de aplica\u00e7\u00e3o da terapia com estrog\u00eanio vaginal diminuem a incid\u00eancia de ITUs recorrentes em mulheres hipoestrog\u00eanicas.<span class=\"citation\">\u2074<\/span> \u00c9 importante destacar que o estrog\u00eanio vaginal aumenta a presen\u00e7a de lactobacilos na vagina, o que ajuda a manter um microbioma vaginal saud\u00e1vel e reduz o risco de ITU.<span class=\"citation\">\u2074<\/span>\n    <\/p>\n    <p>\n        A sele\u00e7\u00e3o de pacientes para a terapia com estrog\u00eanio normalmente envolve uma avalia\u00e7\u00e3o cl\u00ednica dos sintomas e, em alguns casos, estudos urodin\u00e2micos ou cistoscopia, embora o diagn\u00f3stico frequentemente se baseie no quadro cl\u00ednico no contexto da defici\u00eancia de estrog\u00eanio.<span class=\"citation\">\u2075<\/span> Os resultados esperados com o tratamento adequado incluem redu\u00e7\u00e3o dos sintomas urin\u00e1rios, restaura\u00e7\u00e3o de um tecido uretral mais normal e diminui\u00e7\u00e3o da frequ\u00eancia de ITUs.<span class=\"citation\">\u2075<\/span>\n    <\/p>","gt-related-evidence":null,"gt-featured":true,"gt-ai-referenced":false,"gt-view-count":126},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.7 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Estrog\u00eanio na Urologia: Fun\u00e7\u00e3o, Terapia e Aplica\u00e7\u00f5es Cl\u00ednicas<\/title>\n<meta name=\"description\" content=\"O estrog\u00eanio trata atrofia urogenital e reduz ITU recorrente na p\u00f3s-menopausa. Conhe\u00e7a indica\u00e7\u00f5es, terapia vaginal e diretrizes AUA\/EAU atualizadas.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Estrog\u00eanio - Prosthetic Urology Glossary\" \/>\n<meta property=\"og:description\" content=\"Explore Rigicon\u2019s evidence-based glossary covering penile implants, AUS, ED treatments, and surgical terms in prosthetic urology.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/\" \/>\n<meta property=\"og:site_name\" content=\"Rigicon\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/rigiconurology\/\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-06T22:19:32+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.rigicon.com\/wp-content\/uploads\/2025\/05\/header-d.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1440\" \/>\n\t<meta property=\"og:image:height\" content=\"718\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@rigiconurology\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/glossary-term\\\/estrogenio\\\/\",\"url\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/glossary-term\\\/estrogenio\\\/\",\"name\":\"Estrog\u00eanio na Urologia: Fun\u00e7\u00e3o, Terapia e Aplica\u00e7\u00f5es Cl\u00ednicas\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/#website\"},\"datePublished\":\"2025-07-24T14:33:48+00:00\",\"dateModified\":\"2026-10-06T22:19:32+00:00\",\"description\":\"O estrog\u00eanio trata atrofia urogenital e reduz ITU recorrente na p\u00f3s-menopausa. Conhe\u00e7a indica\u00e7\u00f5es, terapia vaginal e diretrizes AUA\\\/EAU atualizadas.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/glossary-term\\\/estrogenio\\\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/glossary-term\\\/estrogenio\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/glossary-term\\\/estrogenio\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"In\u00edcio\",\"item\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Glossary Terms\",\"item\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/urology-glossary\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Estrog\u00eanio\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/#website\",\"url\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/\",\"name\":\"Rigicon\",\"description\":\"Innovative Urological Solutions\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/#organization\"},\"alternateName\":\"Innovative Urological Solutions\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/#organization\",\"name\":\"Rigicon, Inc.\",\"alternateName\":\"Innovative Urological Solutions\",\"url\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.rigicon.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/cropped-Logo-Square-Kopya.jpg\",\"contentUrl\":\"https:\\\/\\\/www.rigicon.com\\\/wp-content\\\/uploads\\\/2024\\\/07\\\/cropped-Logo-Square-Kopya.jpg\",\"width\":512,\"height\":512,\"caption\":\"Rigicon, Inc.\"},\"image\":{\"@id\":\"https:\\\/\\\/www.rigicon.com\\\/pt-br\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/rigiconurology\\\/\",\"https:\\\/\\\/x.com\\\/rigiconurology\",\"https:\\\/\\\/www.instagram.com\\\/rigiconurology\\\/\",\"https:\\\/\\\/www.youtube.com\\\/@Rigicon\\\/podcasts\",\"https:\\\/\\\/www.youtube.com\\\/Rigicon\",\"https:\\\/\\\/www.threads.com\\\/@rigiconurology\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/rigicon\\\/\",\"https:\\\/\\\/www.wikidata.org\\\/wiki\\\/Q141595822\"],\"description\":\"A Rigicon \u00e9 uma fabricante especializada, sediada nos EUA, de dispositivos de urologia prot\u00e9tica: pr\u00f3teses penianas, esf\u00edncteres urin\u00e1rios artificiais e pr\u00f3teses testiculares, comercializados em mais de 75 pa\u00edses.\",\"email\":\"operations@rigicon.com\",\"telephone\":\"+1 (888) 202-9790\",\"legalName\":\"Rigicon, Inc.\",\"vatID\":\"81-3545645\",\"taxID\":\"81-3545645\",\"duns\":\"045247683\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Estrog\u00eanio na Urologia: Fun\u00e7\u00e3o, Terapia e Aplica\u00e7\u00f5es Cl\u00ednicas","description":"O estrog\u00eanio trata atrofia urogenital e reduz ITU recorrente na p\u00f3s-menopausa. Conhe\u00e7a indica\u00e7\u00f5es, terapia vaginal e diretrizes AUA\/EAU atualizadas.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/","og_locale":"pt_BR","og_type":"article","og_title":"Estrog\u00eanio - Prosthetic Urology Glossary","og_description":"Explore Rigicon\u2019s evidence-based glossary covering penile implants, AUS, ED treatments, and surgical terms in prosthetic urology.","og_url":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/","og_site_name":"Rigicon","article_publisher":"https:\/\/www.facebook.com\/rigiconurology\/","article_modified_time":"2026-10-06T22:19:32+00:00","og_image":[{"width":1440,"height":718,"url":"https:\/\/www.rigicon.com\/wp-content\/uploads\/2025\/05\/header-d.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_site":"@rigiconurology","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/","url":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/","name":"Estrog\u00eanio na Urologia: Fun\u00e7\u00e3o, Terapia e Aplica\u00e7\u00f5es Cl\u00ednicas","isPartOf":{"@id":"https:\/\/www.rigicon.com\/pt-br\/#website"},"datePublished":"2025-07-24T14:33:48+00:00","dateModified":"2026-10-06T22:19:32+00:00","description":"O estrog\u00eanio trata atrofia urogenital e reduz ITU recorrente na p\u00f3s-menopausa. Conhe\u00e7a indica\u00e7\u00f5es, terapia vaginal e diretrizes AUA\/EAU atualizadas.","breadcrumb":{"@id":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/estrogenio\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"In\u00edcio","item":"https:\/\/www.rigicon.com\/pt-br\/"},{"@type":"ListItem","position":2,"name":"Glossary Terms","item":"https:\/\/www.rigicon.com\/pt-br\/urology-glossary\/"},{"@type":"ListItem","position":3,"name":"Estrog\u00eanio"}]},{"@type":"WebSite","@id":"https:\/\/www.rigicon.com\/pt-br\/#website","url":"https:\/\/www.rigicon.com\/pt-br\/","name":"Rigicon","description":"Innovative Urological Solutions","publisher":{"@id":"https:\/\/www.rigicon.com\/pt-br\/#organization"},"alternateName":"Innovative Urological Solutions","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.rigicon.com\/pt-br\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"},{"@type":"Organization","@id":"https:\/\/www.rigicon.com\/pt-br\/#organization","name":"Rigicon, Inc.","alternateName":"Innovative Urological Solutions","url":"https:\/\/www.rigicon.com\/pt-br\/","logo":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/www.rigicon.com\/pt-br\/#\/schema\/logo\/image\/","url":"https:\/\/www.rigicon.com\/wp-content\/uploads\/2024\/07\/cropped-Logo-Square-Kopya.jpg","contentUrl":"https:\/\/www.rigicon.com\/wp-content\/uploads\/2024\/07\/cropped-Logo-Square-Kopya.jpg","width":512,"height":512,"caption":"Rigicon, Inc."},"image":{"@id":"https:\/\/www.rigicon.com\/pt-br\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/rigiconurology\/","https:\/\/x.com\/rigiconurology","https:\/\/www.instagram.com\/rigiconurology\/","https:\/\/www.youtube.com\/@Rigicon\/podcasts","https:\/\/www.youtube.com\/Rigicon","https:\/\/www.threads.com\/@rigiconurology","https:\/\/www.linkedin.com\/company\/rigicon\/","https:\/\/www.wikidata.org\/wiki\/Q141595822"],"description":"A Rigicon \u00e9 uma fabricante especializada, sediada nos EUA, de dispositivos de urologia prot\u00e9tica: pr\u00f3teses penianas, esf\u00edncteres urin\u00e1rios artificiais e pr\u00f3teses testiculares, comercializados em mais de 75 pa\u00edses.","email":"operations@rigicon.com","telephone":"+1 (888) 202-9790","legalName":"Rigicon, Inc.","vatID":"81-3545645","taxID":"81-3545645","duns":"045247683"}]}},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.rigicon.com\/pt-br\/wp-json\/wp\/v2\/glossary-term\/12762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rigicon.com\/pt-br\/wp-json\/wp\/v2\/glossary-term"}],"about":[{"href":"https:\/\/www.rigicon.com\/pt-br\/wp-json\/wp\/v2\/types\/glossary-term"}],"wp:attachment":[{"href":"https:\/\/www.rigicon.com\/pt-br\/wp-json\/wp\/v2\/media?parent=12762"}],"wp:term":[{"taxonomy":"glossary-category","embeddable":true,"href":"https:\/\/www.rigicon.com\/pt-br\/wp-json\/wp\/v2\/glossary-category?post=12762"},{"taxonomy":"glossary-product","embeddable":true,"href":"https:\/\/www.rigicon.com\/pt-br\/wp-json\/wp\/v2\/glossary-product?post=12762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}