{"id":12653,"date":"2025-07-09T09:50:23","date_gmt":"2025-07-09T13:50:23","guid":{"rendered":"https:\/\/www.rigicon.com\/glossary-term\/interstitial-cystitis\/"},"modified":"2026-10-06T12:50:55","modified_gmt":"2026-10-06T16:50:55","slug":"cistite-intersticial","status":"publish","type":"glossary-term","link":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/cistite-intersticial\/","title":{"rendered":"Cistite Intersticial"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","glossary-category":[111],"glossary-product":[108,107],"class_list":["post-12653","glossary-term","type-glossary-term","status-publish","hentry","glossary-category-urological-disorders","glossary-product-conticlassic-aus","glossary-product-contireflex-enhanced-aus"],"acf":{"gt-definition":"<p>A cistite intersticial\/s\u00edndrome da bexiga dolorosa (CI\/SBD), anteriormente chamada de cistite intersticial, \u00e9 uma condi\u00e7\u00e3o p\u00e9lvica cr\u00f4nica (dura\u00e7\u00e3o &gt;6 semanas) que afeta ou parece afetar a bexiga urin\u00e1ria, com sintomas de desconforto, press\u00e3o ou dor.<sup>1<\/sup> A condi\u00e7\u00e3o caracteriza-se por inflama\u00e7\u00e3o cr\u00f4nica e sintomas do trato urin\u00e1rio inferior, n\u00e3o decorrentes de infec\u00e7\u00e3o ou de qualquer outra causa claramente identific\u00e1vel.<sup>1,2<\/sup><\/p>\n    \n    <p>A CI\/SBD \u00e9 um dist\u00farbio complexo que envolve o revestimento da bexiga, resultando em desconforto recorrente e frequentemente intenso, urg\u00eancia e aumento da frequ\u00eancia urin\u00e1ria.<sup>3<\/sup> A parede vesical pode apresentar sinais de inflama\u00e7\u00e3o, incluindo \u00falceras de Hunner em alguns pacientes, que s\u00e3o descritas como cicatrizes centrais em \u00e1reas de mucosa eritematosa.<sup>4<\/sup> A camada protetora de glicosaminoglicanos (GAG) da mucosa vesical frequentemente est\u00e1 comprometida em pacientes com CI\/SBD, o que pode permitir que irritantes presentes na urina penetrem na parede vesical e desencadeiem respostas inflamat\u00f3rias.<sup>5<\/sup><\/p>","gt-synonyms":"Cistite Intersticial (CI), S\u00edndrome da Dor na Bexiga (BPS), S\u00edndrome da Bexiga Dolorosa (PBS), S\u00edndrome da Bexiga de Hipersensibilidade, S\u00edndrome Uretral, CI\/BPS","gt-citation":"[1] Lim Y, Leslie SW, O'Rourke S. Interstitial Cystitis\/Bladder Pain Syndrome. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. PMID: 34033350. DOI: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK570588\/\n\n[2] Li J, Yi X, Ai J. Broaden Horizons: The Advancement of Interstitial Cystitis\/Bladder Pain Syndrome. Int J Mol Sci. 2022 Nov 23;23(23):14594. DOI: 10.3390\/ijms232314594. PMID: 36498919; PMCID: PMC9736130.\n\n[3] Windgassen SS, Sutherland S, Finn MTM, et al. Gender differences in the experience of interstitial cystitis\/bladder pain syndrome. Frontiers in Pain Research (Lausanne). 2022;3:954967. DOI: 10.3389\/fpain.2022.954967\n\n[4] Hanno PM, Erickson D, Moldwin R, Faraday MM; American Urological Association. Diagnosis and treatment of interstitial cystitis\/bladder pain syndrome: AUA guideline amendment. J Urol. 2015 May;193(5):1545-53. DOI: 10.1016\/j.juro.2015.01.086. PMID: 25623737.\n\n[5] Akiyama Y, Hanno P. Phenotyping of interstitial cystitis\/bladder pain syndrome. Int J Urol. 2019 Apr;26 Suppl 1:17-19. DOI: 10.1111\/iju.13969. PMID: 30954487.","gt-clinical-context":"<p>A cistite intersticial\/s\u00edndrome da bexiga dolorosa \u00e9 diagnosticada e tratada em contextos cl\u00ednicos quando os pacientes apresentam dor, press\u00e3o ou desconforto vesical cr\u00f4nico percebido como relacionado \u00e0 bexiga urin\u00e1ria, acompanhado de pelo menos um outro sintoma urin\u00e1rio, como urg\u00eancia ou frequ\u00eancia persistentes.<sup>1<\/sup> A condi\u00e7\u00e3o afeta tanto mulheres quanto homens, embora seja mais comumente diagnosticada em mulheres.<sup>3<\/sup><\/p>\n    \n    <p>A sele\u00e7\u00e3o dos pacientes para o diagn\u00f3stico de CI\/SBD normalmente envolve a exclus\u00e3o de outras condi\u00e7\u00f5es com sintomas semelhantes, como infec\u00e7\u00f5es do trato urin\u00e1rio, c\u00e2ncer de bexiga, bexiga hiperativa e, nos homens, prostatite cr\u00f4nica.<sup>1,4<\/sup> O diagn\u00f3stico \u00e9 essencialmente de exclus\u00e3o, o que frequentemente leva a identifica\u00e7\u00e3o tardia ou diagn\u00f3stico incorreto, sobretudo em homens.<sup>1<\/sup><\/p>\n    \n    <p>A avalia\u00e7\u00e3o cl\u00ednica normalmente inclui exames laboratoriais (hemograma completo, painel metab\u00f3lico completo, glicose, HbA1c), exames de urina e uroculturas para descartar outros dist\u00farbios.<sup>1<\/sup> A cistoscopia pode ser apropriada em determinados casos, particularmente em pacientes com mais de 50 anos de idade, que t\u00eam maior probabilidade de apresentar \u00falceras de Hunner, as quais s\u00e3o diagn\u00f3sticas da CI cl\u00e1ssica.<sup>1,4<\/sup><\/p>\n    \n    <p>As abordagens terap\u00eauticas s\u00e3o multimodais e individualizadas, come\u00e7ando com medidas conservadoras, como modifica\u00e7\u00f5es diet\u00e9ticas para evitar irritantes vesicais.<sup>1,4<\/sup> As interven\u00e7\u00f5es farmacol\u00f3gicas podem incluir medicamentos orais (polissulfato s\u00f3dico de pentosana, amitriptilina, anti-histam\u00ednicos), tratamentos intravesicais (dimetilsulf\u00f3xido, heparina, lidoca\u00edna) e, nos casos de \u00falceras de Hunner, fulgura\u00e7\u00e3o ou inje\u00e7\u00e3o de triancinolona.<sup>1,4,5<\/sup><\/p>\n    \n    <p>O progn\u00f3stico da CI\/SBD varia amplamente entre os pacientes. Embora alguns apresentem melhora dos sintomas com o tratamento, outros podem ter sintomas persistentes que impactam significativamente a qualidade de vida, afetando a atividade f\u00edsica, o sono e os relacionamentos \u00edntimos.<sup>3<\/sup><\/p>","gt-related-evidence":null,"gt-featured":true,"gt-ai-referenced":false,"gt-view-count":118},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.7 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Cistite Intersticial: S\u00edndrome da Bexiga Dolorosa | Rigicon<\/title>\n<meta name=\"description\" content=\"Entenda a cistite intersticial\/s\u00edndrome da bexiga dolorosa: sintomas cr\u00f4nicos, diagn\u00f3stico de exclus\u00e3o e tratamento multimodal. 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