{"id":12643,"date":"2025-07-08T10:45:15","date_gmt":"2025-07-08T14:45:15","guid":{"rendered":"https:\/\/www.rigicon.com\/glossary-term\/peyronies-disease-plaque-calcification\/"},"modified":"2026-10-06T18:19:32","modified_gmt":"2026-10-06T22:19:32","slug":"calcificacao-de-placa-na-doenca-de-peyronie","status":"publish","type":"glossary-term","link":"https:\/\/www.rigicon.com\/pt-br\/glossary-term\/calcificacao-de-placa-na-doenca-de-peyronie\/","title":{"rendered":"Calcifica\u00e7\u00e3o de Placa na Doen\u00e7a de Peyronie"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","glossary-category":[135],"glossary-product":[104,105],"class_list":["post-12643","glossary-term","type-glossary-term","status-publish","hentry","glossary-category-peyronies-disease-treatments","glossary-product-infla10-pulse-ipp-series","glossary-product-rigi10-malleable-penile-prosthesis"],"acf":{"gt-definition":"<p>A calcifica\u00e7\u00e3o da placa na doen\u00e7a de Peyronie refere-se \u00e0 forma\u00e7\u00e3o de dep\u00f3sitos endurecidos e mineralizados (calcifica\u00e7\u00e3o) no tecido cicatricial fibroso (placas) que se desenvolve na t\u00fanica albug\u00ednea do p\u00eanis em indiv\u00edduos com doen\u00e7a de Peyronie.<sup>1<\/sup> A doen\u00e7a de Peyronie \u00e9 um dist\u00farbio adquirido do tecido conjuntivo caracterizado por essa forma\u00e7\u00e3o de placas, que pode levar a dor peniana, curvatura e, potencialmente, disfun\u00e7\u00e3o er\u00e9til.<sup>2<\/sup> A calcifica\u00e7\u00e3o da placa \u00e9 uma caracter\u00edstica not\u00e1vel em uma parcela significativa dos casos de doen\u00e7a de Peyronie, e sua presen\u00e7a e extens\u00e3o podem influenciar a gravidade da deformidade peniana e podem afetar as estrat\u00e9gias de tratamento.<sup>1<\/sup>\u02d2<sup>2<\/sup>\u02d2<sup>3<\/sup> As placas calcificadas podem variar de tamanho e s\u00e3o frequentemente identificadas por meio de modalidades de imagem, como a ultrassonografia Doppler duplex peniana.<sup>2<\/sup> As diretrizes da American Urological Association (AUA) tamb\u00e9m reconhecem que as caracter\u00edsticas da placa, incluindo a calcifica\u00e7\u00e3o, s\u00e3o considera\u00e7\u00f5es importantes na avalia\u00e7\u00e3o e no manejo da doen\u00e7a de Peyronie.<sup>4<\/sup><\/p>","gt-synonyms":"Calcifica\u00e7\u00e3o da placa peniana, Placa de Peyronie calcificada, Doen\u00e7a de Peyronie com calcifica\u00e7\u00e3o, Induratio penis plastica com calcifica\u00e7\u00e3o","gt-citation":"[1] Paulis G, Paulis A. Calcification in Peyronie's disease: Its role and clinical influence on the various symptoms and signs of the disease, including psychological impact. Our study of 551 patients. Arch Ital Urol Androl. 2023 Sep 12;95(3):11549. doi: 10.4081\/aiua.2023.11549.\n\n[2] Sandean DP, Leslie SW, Lotfollahzadeh S. Peyronie Disease. [Updated 2024 Oct 6]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK560628\/\n\n[3] Levine LA, Burnett AL. Standard operating procedures for Peyronie's disease. J Sex Med. 2013;10(1):230-244. doi: 10.1111\/j.1743-6109.2012.03003.x. PMID: 23211057.\n\n[4] Nehra A, Alterowitz R, Culkin DJ, et al. Peyronie's Disease: AUA Guideline. J Urol. 2015;194(3):745-753. doi: 10.1016\/j.juro.2015.05.098. (The AUA guideline page itself is the primary source here, the DOI is for the published version of the guideline).\n\n[5] Mian AH, Ziegelmann MJ. Current and Future Directions of Technology in Assessment of Peyronie's Disease. Curr Urol Rep. 2024 Oct 29;26(1):15. doi: 10.1007\/s11934-024-01247-z. PMID: 39470953.\n\n[6] Furtado TP, Osadchiy V, Eleswarapu SV. The Promise of Artificial Intelligence in Peyronie's Disease. Curr Urol Rep. 2024 Sep 21;26(1):3. doi: 10.1007\/s11934-024-01233-5. PMID: 39305366.","gt-clinical-context":"<p>A calcifica\u00e7\u00e3o da placa na doen\u00e7a de Peyronie \u00e9 clinicamente relevante no diagn\u00f3stico, no estadiamento e no manejo da doen\u00e7a de Peyronie (DP).<sup>1<\/sup>\u02d2<sup>2<\/sup>\u02d2<sup>4<\/sup> Ela \u00e9 frequentemente identificada durante o exame f\u00edsico ou, de forma mais definitiva, por meio de exames de imagem, como a ultrassonografia Doppler duplex peniana, e a American Urological Association (AUA) recomenda um teste de inje\u00e7\u00e3o intracavernosa realizado no consult\u00f3rio, com ou sem ultrassonografia Doppler duplex, antes de interven\u00e7\u00f5es invasivas.<sup>2<\/sup>\u02d2<sup>4<\/sup> A presen\u00e7a e a extens\u00e3o da calcifica\u00e7\u00e3o podem influenciar a evolu\u00e7\u00e3o cl\u00ednica e os sintomas do paciente. Por exemplo, estudos sugerem que calcifica\u00e7\u00f5es mais extensas (por exemplo, &gt;1,5 cm ou m\u00faltiplas placas &gt;1,0 cm) podem estar associadas a curvatura peniana mais acentuada e a uma maior probabilidade de necessidade de interven\u00e7\u00e3o cir\u00fargica, mesmo em pacientes com fun\u00e7\u00e3o er\u00e9til satisfat\u00f3ria.<sup>2<\/sup> A calcifica\u00e7\u00e3o tamb\u00e9m \u00e9 uma caracter\u00edstica do subtipo 'doen\u00e7a de Peyronie calcificante' em alguns sistemas de classifica\u00e7\u00e3o cl\u00ednica, que se caracteriza por calcifica\u00e7\u00e3o moderada a grave da placa e pode estar associado \u00e0 progress\u00e3o da doen\u00e7a e \u00e0 dor.<sup>2<\/sup><\/p>\n<p>A sele\u00e7\u00e3o de pacientes para diversos tratamentos pode ser influenciada pela presen\u00e7a de calcifica\u00e7\u00e3o. Embora alguns tratamentos conservadores ou minimamente invasivos sejam tentados, uma calcifica\u00e7\u00e3o significativa pode tornar as placas menos responsivas a determinadas terapias, como as inje\u00e7\u00f5es intralesionais, ou pode ser uma contraindica\u00e7\u00e3o relativa para alguns procedimentos.<sup>4<\/sup> A interven\u00e7\u00e3o cir\u00fargica, incluindo incis\u00e3o\/excis\u00e3o da placa e enxerto ou implante de pr\u00f3tese peniana, \u00e9 frequentemente considerada para pacientes com doen\u00e7a est\u00e1vel, deformidade significativa que dificulta a rela\u00e7\u00e3o sexual e nos quais as medidas conservadoras falharam.<sup>4<\/sup> As diretrizes da AUA fornecem uma estrutura para a sele\u00e7\u00e3o do tratamento com base na estabilidade da doen\u00e7a, na gravidade da curvatura e na fun\u00e7\u00e3o er\u00e9til.<sup>4<\/sup> Por exemplo, a colagenase de Clostridium histolyticum intralesional (onde dispon\u00edvel; foi retirada do mercado europeu) \u00e9 uma op\u00e7\u00e3o para a DP est\u00e1vel com curvatura &gt;30\u00b0 e &lt;90\u00b0 e fun\u00e7\u00e3o er\u00e9til preservada.<sup>4<\/sup> Se houver tamb\u00e9m disfun\u00e7\u00e3o er\u00e9til refrat\u00e1ria \u00e0 terapia medicamentosa, o implante de pr\u00f3tese peniana \u00e9 uma abordagem cir\u00fargica comum, que pode ser combinada com modelagem ou outras manobras de retifica\u00e7\u00e3o.<sup>4<\/sup><\/p>\n<p>Os resultados esperados variam de acordo com a modalidade de tratamento. O objetivo do tratamento \u00e9 reduzir a dor peniana (se presente), corrigir a curvatura peniana para permitir uma rela\u00e7\u00e3o sexual satisfat\u00f3ria e preservar ou restaurar a fun\u00e7\u00e3o er\u00e9til.<sup>4<\/sup> As taxas de sucesso das interven\u00e7\u00f5es cir\u00fargicas s\u00e3o geralmente altas em pacientes adequadamente selecionados, mas as poss\u00edveis complica\u00e7\u00f5es e a necessidade de reabilita\u00e7\u00e3o s\u00e3o considera\u00e7\u00f5es importantes.<sup>2<\/sup>\u02d2<sup>4<\/sup> A presen\u00e7a de calcifica\u00e7\u00e3o extensa pode complicar os procedimentos cir\u00fargicos e pode influenciar a escolha da t\u00e9cnica cir\u00fargica. Por exemplo, placas muito calcificadas podem ser mais dif\u00edceis de incisar ou excisar.<sup>2<\/sup><\/p>","gt-related-evidence":null,"gt-featured":true,"gt-ai-referenced":false,"gt-view-count":142},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.7 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Calcifica\u00e7\u00e3o de Placa na Doen\u00e7a de Peyronie | Rigicon<\/title>\n<meta name=\"description\" content=\"Entenda a calcifica\u00e7\u00e3o da placa na doen\u00e7a de Peyronie: impacto no tratamento, resposta \u00e0 terapia com colagenase e planejamento cir\u00fargico. 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