{"id":12375,"date":"2025-07-23T10:51:10","date_gmt":"2025-07-23T14:51:10","guid":{"rendered":"https:\/\/www.rigicon.com\/glossary-term\/diuretic\/"},"modified":"2026-03-22T06:32:22","modified_gmt":"2026-03-22T10:32:22","slug":"diuretic","status":"publish","type":"glossary-term","link":"https:\/\/www.rigicon.com\/ko\/glossary-term\/diuretic\/","title":{"rendered":"\uc774\ub1e8\uc81c"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","glossary-category":[114],"glossary-product":[],"class_list":["post-12375","glossary-term","type-glossary-term","status-publish","hentry","glossary-category-urological-agents"],"acf":{"gt-definition":"

\uc774\ub1e8\uc81c\ub294 \uccb4\ub0b4 \uc218\ubd84\uacfc \uc804\ud574\uc9c8\uc758 \ubc30\uc124\uc744 \ucd09\uc9c4\ud558\uc5ec \uc18c\ubcc0 \uc0dd\uc131\ub7c9\uacfc \uc18c\ubcc0\ub7c9\uc744 \uc99d\uac00\uc2dc\ud0a4\ub294 \uc57d\ubb3c\uc785\ub2c8\ub2e4.\u00a41<\/sup> \uc774 \uc57d\ubb3c\uc740 \uc8fc\ub85c \uc138\ub1e8\uad00\uc5d0\uc11c \uac00\uc7a5 \ud48d\ubd80\ud55c \uc138\ud3ec\uc678 \uc591\uc774\uc628\uc778 \ub098\ud2b8\ub968(Na+<\/sup>)\uc758 \uc7ac\ud761\uc218\ub97c \uc5b5\uc81c\ud558\uc5ec \uc138\ub1e8\uad00 \ub0b4 \uc0bc\ud22c\uc555\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0 \uacb0\uacfc\uc801\uc73c\ub85c \uc218\ubd84\uc744 \uac10\uc18c\uc2dc\ud0a4\ub294 \uc791\uc6a9\uc744 \ud569\ub2c8\ub2e4. \uc7ac\ud761\uc218.\u00a42<\/sup> \uc774 \uc57d\ub9ac\ud559\uc801 \uc791\uc6a9\uc740 \ubc30\uc124\uc744 \uc704\ud574 \uc2e0\uc7a5\uc561 \uc870\uc808\uc744 \ud6a8\uacfc\uc801\uc73c\ub85c \uae30\uc6b8\uc5ec \uc2e0\uccb4\uc5d0\uc11c \uacfc\ub3c4\ud55c \uc218\ubd84\uc744 \uc81c\uac70\ud558\ub294 \ub370 \ub3c4\uc6c0\uc744 \uc90d\ub2c8\ub2e4.3<\/sup><\/p>\n\n

\uc791\uc6a9 \uba54\ucee4\ub2c8\uc998\uc740 \uc774\ub1e8\uc81c \uc885\ub958\uc5d0 \ub530\ub77c \ub2e4\ub974\uba70, \ub300\ubd80\ubd84\uc740 \uc2e0\uc7a5 \uc138\ub1e8\uad00 \uad00\uac15 \ud45c\uba74\uc5d0 \uc704\uce58\ud55c \ud2b9\uc815 \uc774\uc628 \uc218\uc1a1 \uc218\uc6a9\uccb4\ub97c \ud45c\uc801\uc73c\ub85c \ud569\ub2c8\ub2e4.\u00a44<\/sup> \uac70\uc758 \ubaa8\ub4e0 \uc774\ub1e8\uc81c\ub294 \uc54c\ubd80\ubbfc\uacfc \uacb0\ud569\ub418\uc5b4 \uc788\uc73c\uba70 \uc0ac\uad6c\uccb4 \uc5ec\uacfc\uc5d0\uc11c\ub294 \uc54c\ubd80\ubbfc\uacfc \uac19\uc740 \uac70\ub300\ubd84\uc790\ub97c \uc81c\uc678\ud558\ubbc0\ub85c \uc774\ub1e8\uc81c\ub97c \uad00\uac15\uc73c\ub85c \ud65c\uc131 \ubd84\ube44\ud558\ub294 \uac83\uc774 \uc791\uc6a9\uc758 \uc804\uc81c \uc870\uac74\uc785\ub2c8\ub2e4.5<\/sup> \ub2e4\uc591\ud55c \uc774\ub1e8\uc81c \uc885\ub958 \uc774\ub1e8\uc81c\ub294 \ub2e4\uc74c\uc744 \ud3ec\ud568\ud558\uc5ec \ub124\ud504\ub860\uc744 \ub530\ub77c \ub2e4\ub978 \ubd80\uc704\uc5d0\uc11c \uc791\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n\n <\uc62c>\n

  • \uace0\ub9ac \uc774\ub1e8\uc81c<\/strong>: Henle \uace0\ub9ac\uc758 \ub450\uaebc\uc6b4 \uc0c1\ud589 \uc0ac\uc9c0\uc5d0 \uc788\ub294 Na\u00a4\u00a4\u00a4\u00a4\u00a4\u00a4\u00a4+<\/sup>-2Cl-<\/sup> \uacf5\ub3d9\uc218\uc1a1\uccb4(NKCC2)\uc5d0 \uc791\uc6a9\ud558\uc5ec \ub098\ud2b8\ub968, \uce7c\ub968 \ubc0f \uc5fc\ud654\ubb3c \uc7ac\ud761\uc218\ub97c \ucc28\ub2e8\ud569\ub2c8\ub2e4.6<\/sup> \uc774\ub294 \uace0\uc0bc\ud22c\uc555 \uc218\uc9c8\uc744 \uc0dd\uc131\ud569\ub2c8\ub2e4. \uac04\uc9c8 \ud658\uacbd\uc744 \uc545\ud654\uc2dc\ud0a4\uace0 \uc2e0\uc7a5\uc758 \uc9d1\uc911 \ub2a5\ub825\uc744 \uc800\ud558\uc2dc\ud0b5\ub2c8\ub2e4.<\/li>\n \n
  • \ud2f0\uc544\uc9c0\ub4dc \uc774\ub1e8\uc81c<\/strong>: \uc6d0\uc704 \uc138\ub1e8\uad00\uc758 Na+<\/sup>-Cl-<\/sup> \uacf5\ub3d9\uc218\uc1a1\uccb4\ub97c \uc5b5\uc81c\ud558\uc5ec \ub098\ud2b8\ub968 \ubc0f \uc5fc\ud654\ubb3c \uc7ac\ud761\uc218\ub97c \ubc29\uc9c0\ud569\ub2c8\ub2e4.7<\/sup> \uc774 \uc81c\uc81c\ub294 \ub610\ud55c \uce7c\uc298 \ubcf4\uc720\ub97c \ucd09\uc9c4\ud558\uc5ec \ud2b9\uc815 \uc870\uac74\uc5d0\uc11c \uc720\uc775\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/li>\n \n
  • \uce7c\ub968 \uc808\uc57d \uc774\ub1e8\uc81c<\/strong>: \uc9d1\ud569\uad00\uc758 \uc0c1\ud53c \ub098\ud2b8\ub968 \ucc44\ub110(ENaC)\uc744 \ucc28\ub2e8\ud558\uac70\ub098(\uc608: \uc544\ubc00\ub85c\ub77c\uc774\ub4dc, \ud2b8\ub9ac\uc554\ud14c\ub80c) \uc54c\ub3c4\uc2a4\ud14c\ub860 \uc218\uc6a9\uccb4(\uc608: \uc2a4\ud53c\ub85c\ub178\ub77d\ud1a4, \uc5d0\ud50c\ub808\ub808\ub17c)\ub97c \uae38\ud56d\ud558\uc5ec \uce7c\ub968\uc744 \ubcf4\uc874\ud558\uba74\uc11c \ub098\ud2b8\ub968 \uc7ac\ud761\uc218\ub97c \uc904\uc785\ub2c8\ub2e4.\u00a48<\/sup><\/li>\n \n
  • \ud0c4\uc0b0\ud0c8\uc218\ud6a8\uc18c \uc5b5\uc81c\uc81c<\/strong>: \uadfc\uc704\uc138\ub1e8\uad00\uc758 \ud0c4\uc0b0\ud0c8\uc218\ud6a8\uc18c\ub97c \uc5b5\uc81c\ud558\uc5ec \uc911\ud0c4\uc0b0\uc5fc \uc7ac\ud761\uc218\ub97c \ubc29\ud574\ud558\uace0 \ub098\ud2b8\ub968, \uc911\ud0c4\uc0b0\uc5fc \ubc0f \uc218\ubd84 \ubc30\uc124\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4.\u00a49<\/sup><\/li>\n \n
  • \uc0bc\ud22c\uc131 \uc774\ub1e8\uc81c<\/strong>: \uc804\ud574\uc9c8 \uade0\ud615\uc5d0 \uc601\ud5a5\uc744 \uc8fc\uc9c0 \uc54a\uace0 \uad00\uac15\uc758 \uace0\uc0bc\ud22c\uc555\ub18d\ub3c4\ub97c \uc9c1\uc811 \uc99d\uac00\uc2dc\ucf1c \uc0bc\ud22c\ub97c \ud1b5\ud574 \ubb3c\uc744 \uc138\uad00 \ub0b4\uac15\uc73c\ub85c \ub04c\uc5b4\uc635\ub2c8\ub2e4.\u00a410<\/sup><\/li><\/ol>\n\n

    \uc774\ub1e8\uc81c\uc758 \uc0dd\ub9ac\ud559\uc801 \ud6a8\uacfc\ub294 \ub2e8\uc21c\ud55c \uccb4\uc561 \uc81c\uac70\ub97c \ub118\uc5b4 \uc0b0-\uc5fc\uae30 \uade0\ud615, \uc804\ud574\uc9c8 \ud56d\uc0c1\uc131 \ubc0f \uacbd\uc6b0\uc5d0 \ub530\ub77c \ud608\uad00 \uae34\uc7a5\ub3c4\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uccb4\uc561 \uacfc\ubd80\ud558\ub97c \uc904\uc774\ub294 \ub2a5\ub825\uc73c\ub85c \uc778\ud574 \ubd80\uc885, \uace0\ud608\uc555 \ubc0f \uc804\ud574\uc9c8 \uc7a5\uc560\ub97c \ud2b9\uc9d5\uc73c\ub85c \ud558\ub294 \uc0c1\ud0dc\ub97c \uad00\ub9ac\ud558\ub294 \ub370 \ud544\uc218\uc801\uc778 \uce58\ub8cc\uc81c\uac00 \ub418\uc5c8\uc2b5\ub2c8\ub2e4.\u00a411<\/sup><\/p>

    \uc774\ub1e8\uc81c\ub294 \uc2e0\uc7a5\uc5d0\uc11c \ub098\ud2b8\ub968\uacfc \uc218\ubd84 \ubc30\uc124\uc744 \uc99d\uac00\uc2dc\ud0a4\ub294 \uc57d\ubb3c\uc785\ub2c8\ub2e4. \ube44\ub1e8\uae30\uacfc\uc5d0\uc11c\ub294 \uc694\ub85c\uacb0\uc11d \uc608\ubc29(\ud2f0\uc544\uc9c0\ub4dc \uc774\ub1e8\uc81c), \ubd80\uc885 \uad00\ub9ac, \uace0\ud608\uc555 \uce58\ub8cc \ub4f1\uc5d0 \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \ud2f0\uc544\uc9c0\ub4dc \uc774\ub1e8\uc81c\ub294 \uce7c\uc298 \uc7ac\ud761\uc218\ub97c \ucd09\uc9c4\ud558\uc5ec \uce7c\uc298 \uc694\ub85c\uacb0\uc11d\uc758 \uc7ac\ubc1c\uc744 30-50% \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \ub8e8\ud504 \uc774\ub1e8\uc81c(\ud478\ub85c\uc138\ubbf8\ub4dc)\ub294 \uae09\uc131 \uc694\ud3d0 \uc2dc \uc774\ub1e8 \ucd09\uc9c4\uc5d0 \uc0ac\uc6a9\ub429\ub2c8\ub2e4.<\/p>","gt-synonyms":"\ubb3c\uc57d, \uc774\ub1e8\uc81c, \uc774\ub1e8\uc81c, \uc218\uc561\uc81c, \ub098\ud2b8\ub968\uc774\ub1e8\uc81c, \uc591\uc218\uc81c, \ud56d\uace0\ud608\uc555\uc774\ub1e8\uc81c, \uc2e0\uc7a5\uc774\ub1e8\uc81c, \uc18c\ubcc0\uc790\uadf9\uc81c, \ud0c8\uc218\uc81c","gt-citation":"[1] Arumugham VB, Shahin MH. Therapeutic Uses of Diuretic Agents. StatPearls [Internet]. 2023. DOI: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557838\/\n\n[2] Ellison DH, Felker GM. Diuretic Treatment in Heart Failure. New England Journal of Medicine. 2017;377(20):1964-1975. DOI: 10.1056\/NEJMra1703100\n\n[3] Kehrenberg MCA, Brink A, Malan L, Kruger R. Diuretics: a contemporary pharmacological classification? Frontiers in Pharmacology. 2022;13:883035. DOI: 10.3389\/fphar.2022.883035\n\n[4] Roush GC, Kaur R, Ernst ME. Diuretics: A Review and Update. Journal of Cardiovascular Pharmacology and Therapeutics. 2014;19(1):5-13. DOI: 10.1177\/1074248413497257\n\n[5] Sica DA. Diuretic-Related Side Effects: Development and Treatment. The Journal of Clinical Hypertension. 2007;6(9):532-540. DOI: 10.1111\/j.1524-6175.2004.03789.x\n\n[6] Wilcox CS, Testani JM, Pitt B. Pathophysiology of Diuretic Resistance and Its Implications for the Management of Chronic Heart Failure. Hypertension. 2020;76(4):1045-1054. DOI: 10.1161\/HYPERTENSIONAHA.120.15205\n\n[7] Akbari P, Khorasani-Zadeh A. Thiazide Diuretics. StatPearls [Internet]. 2023. DOI: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532918\/\n\n[8] Felker GM, Ellison DH, Mullens W, Cox ZL, Testani JM. Diuretic Therapy for Patients With Heart Failure: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 2020;75(10):1178-1195. DOI: 10.1016\/j.jacc.2019.12.059\n\n[9] Ellison DH, Sinha AD, Weir MR. Clinical Pharmacology in Diuretic Use. Clinical Journal of the American Society of Nephrology. 2019;14(8):1248-1257. DOI: 10.2215\/CJN.09630818\n\n[10] Novak JE, Inrig JK, Peixoto AJ, Goldstein SL, Weir MR, Sparks MA, Perazella MA, Wilcox CS, Siew ED. Diuretics in States of Volume Overload: Core Curriculum 2022. American Journal of Kidney Diseases. 2022;79(5):731-742. DOI: 10.1053\/j.ajkd.2021.10.013","gt-clinical-context":"

    \uc774\ub1e8\uc81c\ub294 \uccb4\uc561 \uacfc\ubd80\ud558, \uace0\ud608\uc555, \uc804\ud574\uc9c8 \ubd88\uade0\ud615\uc744 \ud2b9\uc9d5\uc73c\ub85c \ud558\ub294 \ub2e4\uc591\ud55c \uc9c8\ud658\uc758 \uad00\ub9ac\ub97c \uc704\ud574 \uc784\uc0c1\uc5d0\uc11c \ub110\ub9ac \uc0ac\uc6a9\ub429\ub2c8\ub2e4.\u00a41<\/sup> \uc774\ub1e8\uc81c\ub294 \uc774\ub1e8\uc81c \uc885\ub958, \ud658\uc790 \ud2b9\uc131, \uae30\ubcf8 \ubcd1\ub9ac\uc0dd\ub9ac\ud559\uc5d0 \ub530\ub77c \ud2b9\uc815 \uc801\uc751\uc99d\uc774 \uacb0\uc815\ub418\ub294 \ub2e4\uc591\ud55c \uc758\ub8cc \uc804\ubb38 \ubd84\uc57c\uc5d0 \uac78\uccd0 \uce58\ub8cc \uc801\uc6a9\ub429\ub2c8\ub2e4.<\/p>\n\n

    \ubd80\uc885\uc131 \uc9c8\ud658<\/h3>\n \n

    \uc2ec\ubd80\uc804<\/h4>\n

    \uc2ec\ubd80\uc804\uc740 \uc774\ub1e8 \uc694\ubc95\uc774 \ud544\uc694\ud55c \uc804\ud615\uc801\uc778 \ubd80\uc885\uc131 \uc9c8\ud658 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4.2<\/sup> \uc2ec\uc7a5 \ud38c\ud551\uc758 \ube44\ud6a8\uc728\uc131\uc740 \uc2e0\uc7a5 \uad00\ub958 \uac10\uc18c\ub85c \uc774\uc5b4\uc838 \ub808\ub2cc-\uc548\uc9c0\uc624\ud150\uc2e0-\uc54c\ub3c4\uc2a4\ud14c\ub860 \uc2dc\uc2a4\ud15c(RAAS)\uc744 \ud65c\uc131\ud654\uc2dc\ud0a4\ub294 \ubc18\uba74, \uc7a5\uae30\uac04 \uc9c0\uc18d\ub418\ub294 \uc815\ub9e5 \uc815\uccb4\ub294 \uac04\uc9c8 \uacf5\uac04\uc73c\ub85c \uccb4\uc561 \uc720\ucd9c\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4.3<\/sup> \uc774\ub7ec\ud55c \uba54\ucee4\ub2c8\uc998\uc740 \ud608\uad00 \ub0b4 \uc6a9\uc801 \ud655\uc7a5\uc744 \ucd08\ub798\ud569\ub2c8\ub2e4. \uccb4\uc911 \uc99d\uac00, \ud638\ud761 \uace4\ub780, \uc804\uc2e0 \ubd80\uc885\uc73c\ub85c \ub098\ud0c0\ub0a9\ub2c8\ub2e4.<\/p>\n \n

    \ub8e8\ud504 \uc774\ub1e8\uc81c, \ud2b9\ud788 \ud478\ub85c\uc138\ubbf8\ub4dc\ub294 \ub354 \ud070 \ud6a8\ub2a5\uc73c\ub85c \uc778\ud574 \uc99d\uc0c1\uc774 \uc788\ub294 \uc2ec\ubd80\uc804 \uce58\ub8cc\uc758 \ucd08\uc11d\uc785\ub2c8\ub2e4.4<\/sup> \uc774\ub7ec\ud55c \uc57d\ubb3c\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \ub0ae\uc740 \uc6a9\ub7c9\uc73c\ub85c \uc2dc\uc791\ud558\uace0 \uc18c\ubcc0\ub7c9\uacfc \uccb4\uc911 \uce21\uc815\uc744 \ud1b5\ud574 \ubaa8\ub2c8\ud130\ub9c1\ud558\uc5ec \uc784\uc0c1 \ubc18\uc751\uc5d0 \ub530\ub77c \uc0c1\ud5a5 \uc870\uc815\ub429\ub2c8\ub2e4.5<\/sup> \uc774\ub1e8\uc81c \uc800\ud56d\uc131\uc758 \uacbd\uc6b0 \ud2f0\uc544\uc9c0\ub4dc \uc774\ub1e8\uc81c(\uc608: \uba54\ud1a8\ub77c\uc874 \ub610\ub294 \ud788\ub4dc\ub85c\ud074\ub85c\ub85c\ud2f0\uc544\uc9c0\ub4dc)\ub97c \ucd94\uac00\ud569\ub2c8\ub2e4. \ub8e8\ud504 \uc774\ub1e8\uc81c\ub294 \uc21c\ucc28\uc801 \ub124\ud504\ub860 \ucc28\ub2e8\uc744 \ud1b5\ud574 \ub098\ud2b8\ub968 \ubc30\uc124\uc744 \uac15\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u00a46<\/sup><\/p>\n \n

    \uc54c\ub3c4\uc2a4\ud14c\ub860 \uc218\uc6a9\uccb4 \uae38\ud56d\uc81c(\uc2a4\ud53c\ub85c\ub178\ub77d\ud1a4, \uc5d0\ud50c\ub808\ub808\ub17c)\ub294 \ud2b9\ud788 NYHA \ud074\ub798\uc2a4 II-IV\uc5d0\uc11c \ubc15\ucd9c\ub960\uc774 35% \ubbf8\ub9cc\uc778 \ud658\uc790\uc758 \uacbd\uc6b0 \uc9c4\ud589\uc131 \uc218\ucd95\uae30 \uc2ec\ubd80\uc804\uc5d0\uc11c \uc0ac\ub9dd\ub960\uacfc \uc774\ud658\uc728 \uc774\uc810\uc744 \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4.7<\/sup> \uc774 \ud6a8\uacfc\ub294 ACE \uc5b5\uc81c\uc81c\uc640 ARB\ub97c \ub9cc\uc131\uc801\uc73c\ub85c \uc0ac\uc6a9\ud558\ub294 \ub3d9\uc548 \uc54c\ub3c4\uc2a4\ud14c\ub860\uc774 \uc5b5\uc81c\uc5d0\uc11c \ubc97\uc5b4\ub098\uae30 \ub54c\ubb38\uc5d0 \ubc1c\uc0dd\ud558\uba70, \uc54c\ub3c4\uc2a4\ud14c\ub860 \uae38\ud56d\uc81c\ub294 \uc774\ub7ec\ud55c \ud604\uc0c1\uc5d0 \ub300\ud55c \ubcf4\ud638\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \ud6a8\uacfc.8<\/sup><\/p>\n \n

    \ubcf5\uc218\ub97c \ub3d9\ubc18\ud55c \uac04\uacbd\ubcc0<\/h4>\n

    \uac04\uacbd\ubcc0\uc131 \ubcf5\uc218\uc758 \uacbd\uc6b0 \uc5fc\ubd84 \uc81c\ud55c\uacfc \uacb0\ud569\ub41c \uc774\ub1e8\uc81c\uac00 1\ucc28 \uce58\ub8cc\ubc95\uc774 \ub429\ub2c8\ub2e4.9<\/sup> \uc2a4\ud53c\ub85c\ub178\ub77d\ud1a4\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \ud56d\uc548\ub4dc\ub85c\uac90 \ud6a8\uacfc\uc640 2\ucc28 \uace0\uc54c\ub3c4\uc2a4\ud14c\ub860\uc99d\uc5d0 \ub300\uc751\ud558\ub294 \ub2a5\ub825\uc73c\ub85c \uc778\ud574 \ucd08\uae30 \uc120\ud0dd \uc57d\ubb3c\uc785\ub2c8\ub2e4.10<\/sup> \uce58\ub8cc\uac00 \uc2e4\ud328\ud558\uac70\ub098 \uc2dc\ub108\uc9c0 \ud6a8\uacfc\ub85c \ub3d9\uc2dc\uc5d0 \uc2dc\uc791\ub420 \uc218 \uc788\ub294 \uacbd\uc6b0 \ub8e8\ud504 \uc774\ub1e8\uc81c\uac00 \ubcf4\uc870 \uc694\ubc95\uc73c\ub85c \ucd94\uac00\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc870\ud569.\u00a411<\/sup> \uac04\uacbd\ubcc0\uc758 \ubcd1\ud0dc\uc0dd\ub9ac\ub294 RAAS \ud65c\uc131\ud654\ub85c \uc778\ud55c \uc2e0\uc7a5 \uae30\ub2a5 \uc7a5\uc560\uc640 \uad00\ub828\ub418\uc5b4 \uccb4\uc561 \uc800\ub958 \uc99d\uac00\uc5d0 \uae30\uc5ec\ud569\ub2c8\ub2e4.12<\/sup><\/p>\n \n

    \uc2e0\uc99d\ud6c4\uad70<\/h4>\n

    \uc800\uc54c\ubd80\ubbfc\ud608\uc99d, \ub2e8\ubc31\ub1e8, \uace0\uc9c0\ud608\uc99d\uc744 \ud2b9\uc9d5\uc73c\ub85c \ud558\ub294 \uc2e0\uc99d\ud6c4\uad70\uc740 \ubd80\uc885\uc744 \uad00\ub9ac\ud558\uae30 \uc704\ud574 \uc774\ub1e8\uc81c \uc694\ubc95\uc774 \ud544\uc694\ud55c \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4.\u00a413<\/sup> \ubd80\uc885 \ud615\uc131 \uba54\ucee4\ub2c8\uc998\uc740 \uc8fc\ub85c \uc9d1\ud569\uad00\uc758 \uc0c1\ud53c \ub098\ud2b8\ub968 \ucc44\ub110(ENaCs) \ud65c\uc131\ud654\uc640 \uad00\ub828\ub418\uba70 RAAS \ud65c\uc131\ud654\ub294 \uc774\ucc28\uc801\uc778 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.14<\/sup> \uc774\ub1e8\uc81c\ub294 \ub2e8\ubc31\uc9c8 \uacb0\ud569\uc131\uc774 \ub192\uae30 \ub54c\ubb38\uc5d0, \uc800\uc54c\ubd80\ubbfc\ud608\uc99d\uc740 \uc138\ub1e8\uad00\uc73c\ub85c\uc758 \ud65c\uc131 \uc57d\ubb3c \uc804\ub2ec\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4. \uc54c\ubd80\ubbfc\uc744 \ud478\ub85c\uc138\ubbf8\ub4dc\uc640 \ubcd1\uc6a9\ud558\uac70\ub098 \ud478\ub85c\uc138\ubbf8\ub4dc\ub97c \ud2b8\ub9ac\uc554\ud14c\ub80c\uacfc \uac19\uc740 ENaC \uc5b5\uc81c\uc81c\uc640 \ubcd1\uc6a9\ud558\uba74 \uc800\uc54c\ubd80\ubbfc\ud608\uc99d \ud658\uc790\uc5d0\uac8c \ud6a8\ub2a5\uc774 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.15<\/sup><\/p>\n \n

    \uace0\ud608\uc555<\/h3>\n

    \ud2f0\uc544\uc9c0\ub4dc \ubc0f \ud2f0\uc544\uc9c0\ub4dc \uc720\uc0ac \uc774\ub1e8\uc81c\ub294 \uc5ec\ub7ec \uc9c0\uce68\uc5d0 \ub530\ub77c \uace0\ud608\uc555 \uad00\ub9ac\ub97c \uc704\ud55c \ucd5c\uc801\uc758 1\ucc28 \uc57d\uc81c\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4.16<\/sup> \ud074\ub85c\ub974\ud0c8\ub9ac\ub3c8\uc740 \ub354 \uae34 \uc791\uc6a9 \uc2dc\uac04\uacfc \ub354 \ub0ae\uc740 \uc6a9\ub7c9\uc5d0\uc11c \ubc18\uac10\uae30\uac00 \uc788\uc5b4 \ub2e4\ub978 \ud56d\uace0\ud608\uc555\uc81c\uc5d0 \ube44\ud574 \uc2ec\ud608\uad00 \uc0ac\uac74 \uc704\ud5d8\uc774 \ud06c\uac8c \uac10\uc18c\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.17<\/sup> \uc778\ub2e4\ud30c\ubbf8\ub4dc\ub294 \uc9c0\uc9c8\uacfc \ud3ec\ub3c4\ub2f9\uc5d0 \ub300\ud55c \uac04\uc12d\uc774 \ucd5c\uc18c\ud654\ub418\uc5b4 \ub2f9\ub1e8\ubcd1 \ud658\uc790\uc5d0\uac8c \uc774\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc2e0\uc9c4\ub300\uc0ac.18<\/sup><\/p>\n \n

    \ud2f0\uc544\uc9c0\ub4dc\uc758 \ud56d\uace0\ud608\uc555 \ud6a8\uacfc\ub294 \ucc98\uc74c\uc5d0\ub294 \ud608\uc7a5\ub7c9\uacfc \uc2ec\ubc15\ucd9c\ub7c9 \uac10\uc18c\uc5d0\uc11c \ube44\ub86f\ub418\uc9c0\ub9cc \uc7a5\uae30\uc801\uc778 \uc774\uc810\uc740 \uc9c1\uc811\uc801\uc778 \ud608\uad00 \ud655\uc7a5 \ud6a8\uacfc\ub97c \ud1b5\ud55c \ub9d0\ucd08 \ud608\uad00 \uc800\ud56d \uac10\uc18c\uc5d0\uc11c \ube44\ub86f\ub429\ub2c8\ub2e4.\u00a419<\/sup> \uace0\ud608\uc555\uc774 \ub9cc\uc131 \uc2e0\uc7a5 \uc9c8\ud658(CKD)\uacfc \uacf5\uc874\ud558\uac70\ub098 \uc0ac\uad6c\uccb4 \uc5ec\uacfc\uc728\uc774 30mL\/\ubd84 \ubbf8\ub9cc\uc73c\ub85c \ub5a8\uc5b4\uc9c0\ub294 \uacbd\uc6b0 \ub8e8\ud504 \uc774\ub1e8\uc81c\uac00 \uc120\ud638\ub420 \uc218 \uc788\uc9c0\ub9cc \ucd5c\uadfc \uc99d\uac70\uc5d0 \ub530\ub974\uba74 \ud2f0\uc544\uc9c0\ub4dc\uac00 \uc5ec\uc804\ud788 \ud6a8\uacfc\uc801\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc124\uc815.20<\/sup> \uce7c\ub968 \uc808\uc57d \uc774\ub1e8\uc81c\ub294 \uce7c\ub968 \ub610\ub294 \ub9c8\uadf8\ub124\uc298\uc774 \uace0\uac08\ub41c \uace0\ud608\uc555 \ud658\uc790\uc5d0\uac8c \uc720\uc6a9\ud569\ub2c8\ub2e4.21<\/sup><\/p>\n \n

    \uae30\ud0c0 \uc784\uc0c1 \uc801\uc6a9<\/h3>\n \n

    \uace0\uce7c\uc298\ub1e8\uc99d \ubc0f \uc2e0\uc7a5\uacb0\uc11d\uc99d<\/h4>\n

    \ud2f0\uc544\uc9c0\ub4dc \uc774\ub1e8\uc81c\ub294 \uce7c\uc298 \uc7ac\ud761\uc218\ub97c \ucd09\uc9c4\ud558\uc5ec \uce7c\uc298 \uc2e0\uacb0\uc11d\uc99d\uc744 \uce58\ub8cc\ud558\uace0 \uc7ac\ubc1c\uc131 \uacb0\uc11d \ud615\uc131\uc744 \uc608\ubc29\ud558\ub294 \ub370 \uc720\uc775\ud569\ub2c8\ub2e4.22<\/sup> \uc774 \uce7c\uc298 \uc720\uc9c0 \ud6a8\uacfc\ub85c \uc778\ud574 \ud2f0\uc544\uc9c0\ub4dc\uac00 \uace8\ub2e4\uacf5\uc99d \uad00\ub9ac\uc5d0\ub3c4 \uc720\uc6a9\ud569\ub2c8\ub2e4.23<\/sup><\/p>\n \n

    \uc694\ubd95\uc99d<\/h4>

    \ud2f0\uc544\uc9c0\ub4dc \uc774\ub1e8\uc81c\ub294 \uc720\ud6a8 \uc21c\ud658\ub7c9 \uac10\uc18c\ub97c \ud1b5\ud574 \uadfc\uc704 \uc138\ub1e8\uad00 \uc218\ubd84 \uc7ac\ud761\uc218\ub97c \ucd09\uc9c4\ud558\uc5ec \uc2e0\uc131 \uc694\ubd95\uc99d\uc758 \ub2e4\ub1e8\ub97c \uc5ed\uc124\uc801\uc73c\ub85c \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.\u00a424<\/sup><\/p>\n \n

    \uae09\uc131 \ud3d0\ubd80\uc885<\/h4>\n

    \uc815\ub9e5 \ub8e8\ud504 \uc774\ub1e8\uc81c\ub294 \uae09\uc131 \ud3d0\ubd80\uc885\uc5d0\uc11c \ube60\ub978 \uc815\ub9e5 \ud655\uc7a5\uacfc \ud6c4\uc18d \uc774\ub1e8\ub97c \uc81c\uacf5\ud558\uc5ec \uc774\ub1e8\uac00 \uc2dc\uc791\ub418\uae30 \uc804\uc5d0 \uc608\uc555\uc744 \uc904\uc774\uace0 \ud638\ud761\uae30 \uc99d\uc0c1\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4.\u00a425<\/sup><\/p>\n \n

    \uace0\uce7c\ub968\ud608\uc99d<\/h4>\n

    \ub8e8\ud504 \ubc0f \ud2f0\uc544\uc9c0\ub4dc \uc774\ub1e8\uc81c\ub294 \uce7c\ub968 \ubc30\uc124\uc744 \uac15\ud654\ud558\uc5ec \uace0\uce7c\ub968\ud608\uc99d \uad00\ub9ac\uc758 \ubcf4\uc870 \uc694\ubc95\uc73c\ub85c \uc0ac\uc6a9\ub429\ub2c8\ub2e4.26<\/sup><\/p>\n \n

    \ub300\uc0ac\uc131 \uc54c\uce7c\ub9ac\uc99d<\/h4>\n

    \ud0c4\uc0b0 \ud0c8\uc218\ud6a8\uc18c \uc5b5\uc81c\uc81c\uc778 \uc544\uc138\ud0c0\uc878\uc544\ubbf8\ub4dc\ub294 \uc911\ud0c4\uc0b0\uc5fc \ubc30\uc124\uc744 \ucd09\uc9c4\ud558\uc5ec \ub300\uc0ac\uc131 \uc54c\uce7c\ub9ac\uc99d \uce58\ub8cc\uc5d0 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4.\u00a427<\/sup><\/p>\n \n

    \uace0\uc0b0\ubcd1<\/h4>\n

    \uc544\uc138\ud0c0\uc878\uc544\ubbf8\ub4dc\ub294 CO2 \uc81c\uac70 \uc99d\uac00\ub97c \ud1b5\ud574 \ud638\ud761\uc131 \uc54c\uce7c\ub9ac\uc99d\uc744 \uc720\ubc1c\ud558\uc5ec \uc870\uc9c1 \uc800\uc0b0\uc18c\uc99d \ubc1c\uc0dd\ub960\uc744 \uac10\uc18c\uc2dc\ud0a4\uae30 \ub54c\ubb38\uc5d0 \uace0\uc0b0\ubcd1 \uc608\ubc29 \ubc0f \uce58\ub8cc\uc5d0 \uc120\ud0dd\ub418\ub294 \uc57d\ubb3c\uc785\ub2c8\ub2e4.\u00a428<\/sup><\/p>\n \n

    \ud658\uc790 \uc120\uc815 \ubc0f \ubaa8\ub2c8\ud130\ub9c1<\/h3>\n

    \uc774\ub1e8\uc81c\ub97c \uc120\ud0dd\ud558\ub824\uba74 \uc2e0\uc7a5 \uae30\ub2a5, \uc804\ud574\uc9c8 \uc0c1\ud0dc, \ub3d9\ubc18 \uc9c8\ud658, \ubcd1\uc6a9 \uc57d\ubb3c \ub4f1 \ud658\uc790\ubcc4 \uc694\uc778\uc744 \uc2e0\uc911\ud558\uac8c \uace0\ub824\ud574\uc57c \ud569\ub2c8\ub2e4.29<\/sup> \uc774\ub1e8\uc81c \uce58\ub8cc \uc911\uc5d0\ub294 \uccb4\uc561 \uc0c1\ud0dc, \uc804\ud574\uc9c8(\ud2b9\ud788 \uce7c\ub968, \ub098\ud2b8\ub968, \ub9c8\uadf8\ub124\uc298), \uc2e0\uc7a5 \uae30\ub2a5 \ubc0f \ud608\uc555\uc744 \uc815\uae30\uc801\uc73c\ub85c \ubaa8\ub2c8\ud130\ub9c1\ud558\ub294 \uac83\uc774 \ud544\uc218\uc801\uc785\ub2c8\ub2e4.30<\/sup> \uc784\uc0c1 \ubc18\uc751 \ubc0f \uc2e4\ud5d8\uc2e4 \ub9e4\uac1c\ubcc0\uc218\uc5d0 \ub530\ub77c \uc6a9\ub7c9 \uc870\uc815\uc774 \ud544\uc694\ud560 \uc218 \uc788\uc73c\uba70 \uc804\ud574\uc9c8\uc744 \ud53c\ud558\ub294 \ub370 \ud2b9\ud788 \uc8fc\uc758\ud574\uc57c \ud569\ub2c8\ub2e4. \ub178\uc778\uacfc \uac19\uc740 \ucde8\uc57d \uacc4\uce35\uc758 \ubd88\uade0\ud615 \ubc0f \ud0c8\uc218.\u00a431<\/sup><\/p>

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