{"id":12366,"date":"2025-07-22T08:26:38","date_gmt":"2025-07-22T12:26:38","guid":{"rendered":"https:\/\/www.rigicon.com\/glossary-term\/antiandrogen\/"},"modified":"2026-10-06T15:38:20","modified_gmt":"2026-10-06T19:38:20","slug":"antiandrogen","status":"publish","type":"glossary-term","link":"https:\/\/www.rigicon.com\/ko\/glossary-term\/antiandrogen\/","title":{"rendered":"\ud56d\uc548\ub4dc\ub85c\uac90"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","glossary-category":[114],"glossary-product":[],"class_list":["post-12366","glossary-term","type-glossary-term","status-publish","hentry","glossary-category-urological-agents"],"acf":{"gt-definition":"<p>\ud56d\uc548\ub4dc\ub85c\uac90\uc740 \uc138\ud3ec \ub0b4 \uc548\ub4dc\ub85c\uac90 \uc218\uc6a9\uccb4\uc5d0 \uacb0\ud569\ud558\uc5ec \uace0\ud658, \ubaa8\ub0ad, \uc2dc\uc0c1\ud558\ubd80, \ub1cc\ud558\uc218\uccb4, \ub09c\uc18c, \uc804\ub9bd\uc120 \ub4f1 \ud45c\uc801 \uc870\uc9c1\uc5d0 \ub300\ud55c \ub0b4\uc778\uc131 \uc548\ub4dc\ub85c\uac90\uc758 \uc791\uc6a9\uc744 \ub9c9\ub294 \uc57d\ubb3c\uc785\ub2c8\ub2e4.<sup>1<\/sup> \uc774 \uc57d\ubb3c\ub4e4\uc740 \uc548\ub4dc\ub85c\uac90\uc774 \uc548\ub4dc\ub85c\uac90 \uc218\uc6a9\uccb4(AR)\uc5d0 \uacb0\ud569\ud558\ub294 \uac83\uc744 \ucc28\ub2e8\ud568\uc73c\ub85c\uc368 \uc548\ub4dc\ub85c\uac90\uc758 \uc791\uc6a9\uc5d0 \uae38\ud56d\ud558\uba70, \uc774\ub97c \ud1b5\ud574 \ud575 \ub0b4 \uc774\ub3d9\uc744 \uc5b5\uc81c\ud558\uc5ec \uc548\ub4dc\ub85c\uac90 \uc2e0\ud638\ub97c \ucc28\ub2e8\ud569\ub2c8\ub2e4.<sup>2<\/sup> \ud56d\uc548\ub4dc\ub85c\uac90\uc740 \uc2a4\ud14c\ub85c\uc774\ub4dc\uc131(\uc608: \uc0ac\uc774\ud504\ub85c\ud14c\ub860 \uc544\uc138\ud14c\uc774\ud2b8)\uacfc \ube44\uc2a4\ud14c\ub85c\uc774\ub4dc\uc131(\ud50c\ub8e8\ud0c0\ubbf8\ub4dc, \ub2d0\ub8e8\ud0c0\ubbf8\ub4dc, \ube44\uce7c\ub8e8\ud0c0\ubbf8\ub4dc, \uc5d4\uc798\ub8e8\ud0c0\ub9c8\uc774\ub4dc, \uc544\ud314\ub8e8\ud0c0\ub9c8\uc774\ub4dc, \ub2e4\ub864\ub8e8\ud0c0\ub9c8\uc774\ub4dc \ud3ec\ud568)\uc73c\ub85c \ubd84\ub958\ub429\ub2c8\ub2e4.<sup>3<\/sup> \uc2e0\uc138\ub300 \ud56d\uc548\ub4dc\ub85c\uac90(\uc5d4\uc798\ub8e8\ud0c0\ub9c8\uc774\ub4dc, \uc544\ud314\ub8e8\ud0c0\ub9c8\uc774\ub4dc, \ub2e4\ub864\ub8e8\ud0c0\ub9c8\uc774\ub4dc)\uc740 AR\uc5d0 \ub300\ud55c \uce5c\ud654\ub3c4\uac00 \ub354 \ub192\uc544 \uc548\ub4dc\ub85c\uac90 \ucc28\ub2e8 \ud6a8\uacfc\ub97c \ucd5c\uc801\ud654\ud569\ub2c8\ub2e4.<sup>4<\/sup> \ud56d\uc548\ub4dc\ub85c\uac90\uc740 \uc8fc\ub85c \uc804\ub9bd\uc120\uc554 \uce58\ub8cc\uc5d0 \uc0ac\uc6a9\ub418\uc9c0\ub9cc, \uc548\ub4dc\ub85c\uac90 \uc791\uc6a9\uc744 \uc904\uc774\ub294 \uac83\uc774 \uc720\uc775\ud55c \ub2e4\ub978 \uc9c8\ud658\uc5d0\ub3c4 \uc0ac\uc6a9\ub429\ub2c8\ub2e4.<sup>5<\/sup><\/p>","gt-synonyms":"\uc548\ub4dc\ub85c\uac90 \uc218\uc6a9\uccb4 \uae38\ud56d\uc81c, \uc548\ub4dc\ub85c\uac90 \uc218\uc6a9\uccb4 \ucc28\ub2e8\uc81c, \ud14c\uc2a4\ud1a0\uc2a4\ud14c\ub860 \ucc28\ub2e8\uc81c, AR \uc5b5\uc81c\uc81c, \uc548\ub4dc\ub85c\uac90 \uae38\ud56d\uc81c","gt-citation":"[1] Lanz C, Bennamoun M, Macek P, Cathelineau X, Sanchez-Salas R. The importance of antiandrogen in prostate cancer treatment. Ann Transl Med. 2019;7(Suppl 8):S362. DOI: 10.21037\/atm.2019.09.53\n\n[2] National Cancer Institute. Hormone Therapy for Prostate Cancer Fact Sheet. Updated October 4, 2024. https:\/\/www.cancer.gov\/types\/prostate\/prostate-hormone-therapy-fact-sheet\n\n[3] LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2014. Antiandrogens. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK548491\/\n\n[4] Gao W, Mahto M. Commercial Antiandrogens. In: Understanding Cancer, 2016. https:\/\/www.sciencedirect.com\/topics\/agricultural-and-biological-sciences\/antiandrogen\n\n[5] American Cancer Society. Hormone Therapy for Prostate Cancer. 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\uae30\uac04\uc744 \uc5f0\uc7a5\ud558\ub294 \uac83\uc73c\ub85c \ubcf4\uace0\ub41c \ubc18\uba74, \ube44\uce7c\ub8e8\ud0c0\ubbf8\ub4dc\ub294 \ubcf4\ub2e4 \uc81c\ud55c\uc801\uc778 \uc774\uc810\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4.<sup>4<\/sup><\/p>\n    \n    <p>\uc2e0\uc138\ub300 \ud56d\uc548\ub4dc\ub85c\uac90(\uc5d4\uc798\ub8e8\ud0c0\ub9c8\uc774\ub4dc, \uc544\ud314\ub8e8\ud0c0\ub9c8\uc774\ub4dc, \ub2e4\ub864\ub8e8\ud0c0\ub9c8\uc774\ub4dc)\uc740 \ub354 \ub192\uc740 \ud6a8\ub2a5\uc744 \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uc5d4\uc798\ub8e8\ud0c0\ub9c8\uc774\ub4dc\ub294 \uc804\uc774\uc131 \uac70\uc138 \uc800\ud56d\uc131 \uc804\ub9bd\uc120\uc554\uc5d0\uc11c \ud56d\uc554\ud654\ud559\uc694\ubc95 \uc804\ud6c4 \ubaa8\ub450 \uc804\uccb4 \uc0dd\uc874 \uae30\uac04 \uac1c\uc120\uc744 \ubcf4\uc600\uace0(PREVAIL \ubc0f AFFIRM \uc2dc\ud5d8), \ube44\uc804\uc774\uc131 \uac70\uc138 \uc800\ud56d\uc131 \uc804\ub9bd\uc120\uc554\uc5d0\uc11c\ub294 \ubb34\uc804\uc774 \uc0dd\uc874 \uae30\uac04 \uac1c\uc120\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4(PROSPER \uc2dc\ud5d8).<sup>5<\/sup> \ub9c8\ucc2c\uac00\uc9c0\ub85c \uc544\ud314\ub8e8\ud0c0\ub9c8\uc774\ub4dc\ub294 \uc804\uc774 \ubc1c\uc0dd \uc704\ud5d8\uc774 \ub192\uc740 \ube44\uc804\uc774\uc131 \uac70\uc138 \uc800\ud56d\uc131 \uc804\ub9bd\uc120\uc554 \ub0a8\uc131\uc5d0\uc11c \ubb34\uc804\uc774 \uc0dd\uc874 \uae30\uac04 \uac1c\uc120\uc744 \uc785\uc99d\ud588\uc2b5\ub2c8\ub2e4(SPARTAN \uc2dc\ud5d8).<sup>6<\/sup><\/p>\n    \n    <p>\ud56d\uc548\ub4dc\ub85c\uac90 \uc694\ubc95\uc758 \ud658\uc790 \uc120\ubcc4\uc740 \uc804\ub9bd\uc120\uc554\uc758 \ubcd1\uae30\uc640 \ud2b9\uc131\uc5d0 \ub530\ub77c \ub2ec\ub77c\uc9d1\ub2c8\ub2e4. \uad6d\uc81c \uac00\uc774\ub4dc\ub77c\uc778(EAU, NCCN, AUA)\uc5d0 \ub530\ub974\uba74, \ud56d\uc548\ub4dc\ub85c\uac90\uc740 \uc804\uc774 \uc704\ud5d8\uc774 \ub192\uc740 \ube44\uc804\uc774\uc131 \uac70\uc138 \uc800\ud56d\uc131 \uc804\ub9bd\uc120\uc554 \ud658\uc790\ubfd0 \uc544\ub2c8\ub77c 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