{"id":12316,"date":"2025-07-08T10:12:16","date_gmt":"2025-07-08T14:12:16","guid":{"rendered":"https:\/\/www.rigicon.com\/glossary-term\/klinefelter-syndrome\/"},"modified":"2026-10-06T15:38:20","modified_gmt":"2026-10-06T19:38:20","slug":"klinefelter-syndrome","status":"publish","type":"glossary-term","link":"https:\/\/www.rigicon.com\/ko\/glossary-term\/klinefelter-syndrome\/","title":{"rendered":"\ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","glossary-category":[139],"glossary-product":[116],"class_list":["post-12316","glossary-term","type-glossary-term","status-publish","hentry","glossary-category-congenital-urological-anomalies","glossary-product-testi10-testicular-prosthesis"],"acf":{"gt-definition":"<p>\ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70(47,XXY\ub77c\uace0\ub3c4 \ud568)\uc740 \ub0a8\uc131\uc758 \uc2e0\uccb4\uc801\u00b7\uc9c0\uc801 \ubc1c\ub2ec\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uc720\uc804\uc801 \ub610\ub294 \uc5fc\uc0c9\uccb4 \uc9c8\ud658\uc785\ub2c8\ub2e4. \ub0a8\uc131\uc774 \uc5ec\ubd84\uc758 X \uc5fc\uc0c9\uccb4\ub97c \uac00\uc9c0\uace0 \ud0dc\uc5b4\ub0a0 \ub54c \ubc1c\uc0dd\ud569\ub2c8\ub2e4. \uc815\uc0c1\uc801\uc73c\ub85c \uc5ec\uc131\uc740 \ub450 \uac1c\uc758 X \uc5fc\uc0c9\uccb4(XX)\ub97c, \ub0a8\uc131\uc740 \ud558\ub098\uc758 X \uc5fc\uc0c9\uccb4\uc640 \ud558\ub098\uc758 Y \uc5fc\uc0c9\uccb4(XY)\ub97c \uac00\uc9d1\ub2c8\ub2e4. \ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70\uc5d0\uc11c\ub294 \ub0a8\uc131\uc774 \ucd5c\uc18c \ub450 \uac1c\uc758 X \uc5fc\uc0c9\uccb4\uc640 \ucd5c\uc18c \ud558\ub098\uc758 Y \uc5fc\uc0c9\uccb4\ub97c \uac00\uc9d1\ub2c8\ub2e4(\uac00\uc7a5 \ud754\ud558\uac8c\ub294 XXY).<sup>1<\/sup> \uc774 \uc5ec\ubd84\uc758 \uc720\uc804 \ubb3c\uc9c8\uc740 \ub2e4\uc591\ud55c \uc2e0\uccb4\uc801, \ubc1c\ub2ec\uc801, \uc778\uc9c0\uc801 \ud2b9\uc131\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5ec\ubd84\uc758 X \uc5fc\uc0c9\uccb4\uac00 \ubbf8\uce58\ub294 \uc8fc\ub41c \uc601\ud5a5\uc740 \uace0\ud658 \ubc1c\ub2ec\uc5d0 \ub300\ud55c \uac83\uc73c\ub85c, \uace0\ud658\uc774 \ud3c9\uade0\ubcf4\ub2e4 \uc791\uc544\uc9c0\uace0 \uc8fc\uc694 \ub0a8\uc131 \uc131\ud638\ub974\ubaac\uc778 \ud14c\uc2a4\ud1a0\uc2a4\ud14c\ub860\uc758 \uc0dd\uc131\uc774 \uac10\uc18c\ud569\ub2c8\ub2e4.<sup>2<\/sup> \ud14c\uc2a4\ud1a0\uc2a4\ud14c\ub860\uc740 \ucd9c\uc0dd \uc804\uacfc \uc0ac\ucd98\uae30 \ub3d9\uc548 \ub0a8\uc131\uc758 \uc131\uc801 \ubc1c\ub2ec\uc5d0 \ub9e4\uc6b0 \uc911\uc694\ud558\uba70, \uadfc\uc721\ub7c9, \uace8\ubc00\ub3c4, \uc5bc\uad74 \ud138\uacfc \uccb4\ubaa8, \uc131\uc695\uacfc \uac19\uc740 \ud2b9\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4.<sup>3<\/sup> \uc5ec\ubd84\uc758 X \uc5fc\uc0c9\uccb4\uac00 \uc874\uc7ac\ud558\uba74 \uace0\ud658\uc758 \uc815\uc0c1\uc801\uc778 \uae30\ub2a5\uc774 \ubc29\ud574\ub97c \ubc1b\uc544 \ud754\ud788 \uc6d0\ubc1c\uc131 \uace0\ud658 \uae30\ub2a5\ubd80\uc804\uc774 \ubc1c\uc0dd\ud558\uba70, \uc774\ub294 \uace0\ud658\uc774 \ucda9\ubd84\ud55c \ud14c\uc2a4\ud1a0\uc2a4\ud14c\ub860\uc774\ub098 \uc815\uc790\ub97c \uc0dd\uc131\ud558\uc9c0 \ubabb\ud55c\ub2e4\ub294 \uc758\ubbf8\uc785\ub2c8\ub2e4.<sup>1<\/sup> \uc774\ub85c \uc778\ud574 \uc0ac\ucd98\uae30 \uc9c0\uc5f0 \ub610\ub294 \ubd88\uc644\uc804 \uc0ac\ucd98\uae30, \uc0dd\uc2dd\ub2a5\ub825 \uc800\ud558 \ub610\ub294 \ubd88\uc784, \uadf8\ub9ac\uace0 \uc5ec\uc131\ud615 \uc720\ubc29(\uc720\ubc29 \uc870\uc9c1 \ube44\ub300)\uacfc \uac19\uc740 \uae30\ud0c0 \uc2e0\uccb4\uc801 \ud2b9\uc9d5\uc774 \ub098\ud0c0\ub0a0 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<sup>2<\/sup><\/p>","gt-synonyms":"","gt-citation":"[1] National Center for Biotechnology Information (NCBI). Klinefelter Syndrome - StatPearls. National Library of Medicine. Updated May 5, 2025. Accessed May 15, 2025. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK482314\/\n\n[2] Mayo Clinic Staff. Klinefelter syndrome. Mayo Clinic. Published October 29, 2024. Accessed May 15, 2025. https:\/\/www.mayoclinic.org\/diseases-conditions\/klinefelter-syndrome\/symptoms-causes\/syc-20353949\n\n[3] MedlinePlus. Klinefelter syndrome. National Library of Medicine. Updated July 10, 2023. Accessed May 15, 2025. https:\/\/medlineplus.gov\/genetics\/condition\/klinefelter-syndrome\/\n\n[4] Cleveland Clinic. Klinefelter Syndrome. Cleveland Clinic. Last reviewed January 26, 2023. Accessed May 15, 2025. https:\/\/my.clevelandclinic.org\/health\/diseases\/21116-klinefelter-syndrome\n\n[5] Visootsak J, Graham JM Jr. Klinefelter syndrome and other sex chromosomal aneuploidies. Orphanet J Rare Dis. 2006;1:42. doi:10.1186\/1750-1172-1-42","gt-clinical-context":"<p>\ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \ud2b9\uc9d5\uc801\uc778 \uc9d5\ud6c4\uc640 \uc99d\uc0c1\uc774 \ubcf5\ud569\uc801\uc73c\ub85c \ub098\ud0c0\ub0a0 \ub54c \uc784\uc0c1 \ud658\uacbd\uc5d0\uc11c \ud655\uc778\ub418\uace0 \uad00\ub9ac\ub418\uba70, \uc0b0\uc804 \uc720\uc804 \uc120\ubcc4\uac80\uc0ac \uc911\uc774\ub098 \uc774\ud6c4 \ubd88\uc784 \uac80\uc0ac \uc911\uc5d0 \uc6b0\uc5f0\ud788 \ubc1c\uacac\ub420 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4.<sup>1<\/sup>\u02d2<sup>2<\/sup> \uc784\uc0c1\uc801\uc73c\ub85c\ub294 \uc5b8\uc5b4, \ub9d0\ud558\uae30 \ub610\ub294 \uc6b4\ub3d9 \uae30\uc220\uc758 \uc9c0\uc5f0, \uadfc\uae34\uc7a5 \uc800\ud558, \ud559\uc2b5 \uc7a5\uc560\uc640 \uac19\uc740 \ubc1c\ub2ec \uc9c0\uc5f0\uc774 \uc788\ub294 \uacbd\uc6b0 \uc601\uc544\uae30\ub098 \uc18c\uc544\uae30\uc5d0 \uc9c4\ub2e8\uc774 \uc758\uc2ec\ub418\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4.<sup>3<\/sup> \uccad\uc18c\ub144\uae30\uc5d0\ub294 \uc791\uc740 \uace0\ud658(\uc65c\uc18c\uc74c\uacbd\uc774 \ub3d9\ubc18\ub420 \uc218\ub3c4 \uc788\uc74c), \uc5bc\uad74 \ud138\uacfc \uccb4\ubaa8 \uac10\uc18c, \uadfc\uc721\uc774 \uc801\uc740 \uccb4\ud615, \uc5ec\uc131\ud615 \uc720\ubc29(\uc720\ubc29 \uc870\uc9c1 \ube44\ub300) \ubc1c\uc0dd \ub4f1 \uc0ac\ucd98\uae30 \uc9c0\uc5f0 \ub610\ub294 \ubd88\uc644\uc804 \uc0ac\ucd98\uae30 \uc9d5\ud6c4\uc640 \ud568\uaed8 \ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70\uc774 \ub354 \ub69c\ub837\ud574\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<sup>1<\/sup>\u02d2<sup>4<\/sup> \uc131\uc778\uae30\uc5d0\ub294 \ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70\uc774 \uc788\ub294 \uc0ac\ub78c \ub300\ubd80\ubd84\uc774 \uc815\uc790 \uc0dd\uc131\uc774 \ud604\uc800\ud788 \uac10\uc18c(\ubb34\uc815\uc790\uc99d \ub610\ub294 \uc911\uc99d \ud54d\uc815\uc790\uc99d)\ub418\uc5b4 \uc788\uae30 \ub54c\ubb38\uc5d0, \uc784\uc0c1\uc801\uc73c\ub85c \ub0b4\uc6d0\ud558\uc5ec \uc9c4\ub2e8\ubc1b\ub294 \uac00\uc7a5 \ud754\ud55c \uc774\uc720\ub294 \ubd88\uc784\uc785\ub2c8\ub2e4.<sup>2<\/sup>\u02d2<sup>3<\/sup><\/p>\n<p>\ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70\uc758 \ud3c9\uac00 \ubc0f \uad00\ub9ac\ub97c \uc704\ud55c \ud658\uc790 \uc120\ud0dd\uc740 \uc8fc\ub85c \uc55e\uc11c \uc5b8\uae09\ud55c \uc2e0\uccb4\uc801, \ubc1c\ub2ec\uc801 \ub610\ub294 \uc0dd\uc2dd\uc801 \ud2b9\uc9d5\uc744 \ubcf4\uc774\ub294 \ub0a8\uc131\uc744 \ub300\uc0c1\uc73c\ub85c \ud569\ub2c8\ub2e4. \ud655\uc9c4\uc740 \ud575\ud615 \ubd84\uc11d\uc744 \ud1b5\ud574 \uc774\ub8e8\uc5b4\uc9c0\uba70, \uc774\ub97c \ud1b5\ud574 \uc5ec\ubd84\uc758 X \uc5fc\uc0c9\uccb4(\uc608: 47,XXY)\uc758 \uc874\uc7ac\uac00 \ud655\uc778\ub429\ub2c8\ub2e4.<sup>1<\/sup> \ud638\ub974\ubaac \uac80\uc0ac\uc5d0\uc11c\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \ub0ae\uac70\ub098 \uc815\uc0c1 \ud558\ud55c\uc758 \ud14c\uc2a4\ud1a0\uc2a4\ud14c\ub860 \uc218\uce58, \uc0c1\uc2b9\ub41c \ub09c\ud3ec\uc790\uadf9\ud638\ub974\ubaac(FSH) \ubc0f \ud669\uccb4\ud615\uc131\ud638\ub974\ubaac(LH) \uc218\uce58, \uadf8\ub9ac\uace0 \ud754\ud788 \uc0c1\uc2b9\ub41c \uc5d0\uc2a4\ud2b8\ub77c\ub514\uc62c \uc218\uce58\uac00 \ub098\ud0c0\ub098\uba70, \uc774\ub294 \uc6d0\ubc1c\uc131 \uace0\ud658 \uae30\ub2a5\ubd80\uc804(\uace0\uc131\uc120\uc790\uadf9\ud638\ub974\ubaac\uc131 \uc131\uc120\uae30\ub2a5\uc800\ud558\uc99d)\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<sup>1<\/sup>\u02d2<sup>4<\/sup><\/p>\n<p>\ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70\uc5d0\ub294 \uc5ec\ub7ec \uc9c8\ud658\uc774 \ud754\ud788 \ub3d9\ubc18\ub418\ubbc0\ub85c \uc9c0\uc18d\uc801\uc778 \uc784\uc0c1\uc801 \ubaa8\ub2c8\ud130\ub9c1\uacfc \uad00\ub9ac\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc5ec\uae30\uc5d0\ub294 \uc131\uc120\uae30\ub2a5\uc800\ud558\uc99d, \ubd88\uc784, \ub0ae\uc740 \ud14c\uc2a4\ud1a0\uc2a4\ud14c\ub860\uc73c\ub85c \uc778\ud55c \uace8\ub2e4\uacf5\uc99d \ub610\ub294 \uace8\uac10\uc18c\uc99d, \ub300\uc0ac\uc99d\ud6c4\uad70(\ube44\ub9cc, \uc81c2\ud615 \ub2f9\ub1e8\ubcd1, \uace0\ud608\uc555, \uc774\uc0c1\uc9c0\uc9c8\ud608\uc99d \ud3ec\ud568), \uc790\uac00\uba74\uc5ed \uc9c8\ud658(\ub8e8\ud478\uc2a4, \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc \ub4f1)\uc758 \uc704\ud5d8 \uc99d\uac00, \uc815\ub9e5 \ud608\uc804\uc0c9\uc804\uc99d, \uadf8\ub9ac\uace0 \ud2b9\uc815 \uc720\ud615\uc758 \uc554, \ud2b9\ud788 \uc720\ubc29\uc554\uacfc \uc0dd\uc2dd\uc120\uc678 \uc0dd\uc2dd\uc138\ud3ec \uc885\uc591\uc774 \ud3ec\ud568\ub429\ub2c8\ub2e4.<sup>1<\/sup>\u02d2<sup>2<\/sup>\u02d2<sup>3<\/sup>\u02d2<sup>4<\/sup> \ud559\uc2b5 \uc7a5\uc560(\ud2b9\ud788 \uc5b8\uc5b4 \uae30\ubc18 \uae30\uc220\uacfc \uc2e4\ud589 \uae30\ub2a5), \uc8fc\uc758\ub825\uacb0\ud54d \uacfc\uc789\ud589\ub3d9\uc7a5\uc560(ADHD), \ubd88\uc548, \uc6b0\uc6b8\uc99d, \uc790\ud3d0 \uc2a4\ud399\ud2b8\ub7fc \uc7a5\uc560 \uc720\ubcd1\ub960 \uc99d\uac00 \ub4f1 \uc2e0\uacbd\uc2ec\ub9ac\ud559\uc801 \ubb38\uc81c\ub3c4 \ud754\ud569\ub2c8\ub2e4.<sup>1<\/sup>\u02d2<sup>3<\/sup><\/p>\n<p>\ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70\uc758 \ud2b9\uc815 \uce21\uba74\uc744 \uad00\ub9ac\ud558\uae30 \uc704\ud574 \uc218\uc220\uc801 \uc2dc\uc220\uc744 \uace0\ub824\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc2ec\ud558\uac70\ub098 \ubd88\ud3b8\ud55c \uc5ec\uc131\ud615 \uc720\ubc29\uc758 \uacbd\uc6b0 \uc218\uc220\uc801 \uc720\ubc29 \uc870\uc9c1 \uc81c\uac70(\uc720\ubc29 \ucd95\uc18c\uc220)\ub97c \uc2dc\ud589\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<sup>2<\/sup> \uc790\uc5f0\uc801\uc73c\ub85c \ud574\uc18c\ub418\uc9c0 \uc54a\ub294 \uc7a0\ubcf5\uace0\ud658(\ubbf8\ud558\uac15 \uace0\ud658)\uc774 \uc788\ub294 \uacbd\uc6b0 \uc601\uc544\uae30\ub098 \ucd08\uae30 \uc18c\uc544\uae30\uc5d0 \uace0\ud658\uace0\uc815\uc220\uc774 \ud544\uc694\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<sup>1<\/sup> \ubd88\uc784\uacfc \uad00\ub828\ud574\uc11c\ub294 \uace0\ud658 \uc815\uc790 \ucd94\ucd9c\uc220(TESE), \ud754\ud788 \ubbf8\uc138\uc808\uac1c TESE(micro-TESE)\uc640 \uac19\uc740 \ucca8\ub2e8 \uc0dd\uc2dd \uae30\ubc95\uc744 \ud65c\uc6a9\ud558\uc5ec \ub09c\uc790 \uc138\ud3ec\uc9c8 \ub0b4 \uc815\uc790 \uc8fc\uc785\uc220(ICSI)\uc5d0 \uc0ac\uc6a9\ud560 \uc815\uc790\ub97c \ucc44\ucde8\ud560 \uc218 \uc788\uc73c\uba70, \uc774\ub97c \ud1b5\ud574 \ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70 \ub0a8\uc131 \uc911 \uc77c\ubd80\ub294 \uc0dd\ubb3c\ud559\uc801 \uc544\ubc84\uc9c0\uac00 \ub420 \uae30\ud68c\ub97c \uc5bb\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<sup>1<\/sup>\u02d2<sup>4<\/sup><\/p>\n<p>\ud074\ub77c\uc778\ud3a0\ud130 \uc99d\ud6c4\uad70\uc774 \uc788\ub294 \uc0ac\ub78c\uc758 \uc608\uc0c1 \uacb0\uacfc\ub294 \ub2e4\uc591\ud558\uba70, \uc9c4\ub2e8 \uc2dc \uc5f0\ub839, \uc99d\uc0c1\uc758 \uc911\uc99d\ub3c4, \uad00\ub9ac\uc758 \uc77c\uad00\uc131\uc5d0 \ud06c\uac8c \uc88c\uc6b0\ub429\ub2c8\ub2e4. \uc0ac\ucd98\uae30 \ubb34\ub835\uc5d0 \uc2dc\uc791\ud558\ub294 \ud14c\uc2a4\ud1a0\uc2a4\ud14c\ub860 \ub300\uccb4 \uc694\ubc95(TRT)\uc744 \ud3ec\ud568\ud55c \uc870\uae30 \uc9c4\ub2e8\uacfc \uc911\uc7ac\ub294 \uc815\uc0c1\uc801\uc778 \ub0a8\uc131\ud654\ub97c \ucd09\uc9c4\ud558\uace0, \uace8\ubc00\ub3c4\ub97c \uac1c\uc120\ud558\uba70, \uadfc\uc721\ub7c9\uc744 \ub298\ub9ac\uace0, \uae30\ubd84\uacfc \ud65c\ub825\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc73c\uba70, \uc77c\ubd80 \uc778\uc9c0 \ubc0f \ud589\ub3d9\uc0c1\uc758 \uc5b4\ub824\uc6c0\uc744 \uc644\ud654\ud560 \uac00\ub2a5\uc131\ub3c4 \uc788\uc2b5\ub2c8\ub2e4.<sup>1<\/sup>\u02d2<sup>2<\/sup> \uadf8\ub7ec\ub098 TRT\ub294 \uc0dd\uc2dd\ub2a5\ub825\uc744 \ud68c\ubcf5\uc2dc\ud0a4\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4.<sup>4<\/sup> \uc5b8\uc5b4\uce58\ub8cc, \ubb3c\ub9ac\uce58\ub8cc, \uc791\uc5c5\uce58\ub8cc \ubc0f \uad50\uc721\uc801 \uc9c0\uc6d0\uc744 \ud1b5\ud574 \ubc1c\ub2ec \uc9c0\uc5f0\uacfc \ud559\uc2b5\uc0c1\uc758 \uc5b4\ub824\uc6c0\uc5d0 \ub300\ucc98\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<sup>3<\/sup> 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