{"id":12124,"date":"2025-07-25T09:58:14","date_gmt":"2025-07-25T13:58:14","guid":{"rendered":"https:\/\/www.rigicon.com\/glossary-term\/hormone-therapy\/"},"modified":"2026-10-06T18:04:24","modified_gmt":"2026-10-06T22:04:24","slug":"terapia-hormonal","status":"publish","type":"glossary-term","link":"https:\/\/www.rigicon.com\/es\/glossary-term\/terapia-hormonal\/","title":{"rendered":"Terapia Hormonal"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","glossary-category":[137],"glossary-product":[],"class_list":["post-12124","glossary-term","type-glossary-term","status-publish","hentry","glossary-category-hormone-therapy"],"acf":{"gt-definition":"<p>\n        La terapia hormonal, tambi\u00e9n denominada terapia de privaci\u00f3n androg\u00e9nica (TPA), es un enfoque terap\u00e9utico que tiene como objetivo reducir los niveles de hormonas masculinas (andr\u00f3genos) en el organismo o impedir que estimulen el crecimiento de las c\u00e9lulas del c\u00e1ncer de pr\u00f3stata.<span class=\"citation\">1<\/span> Esta estrategia terap\u00e9utica act\u00faa impidiendo que el organismo produzca testosterona, bloqueando la acci\u00f3n de los andr\u00f3genos en todo el cuerpo o inhibiendo la producci\u00f3n de andr\u00f3genos en diversos tejidos, incluidas las propias c\u00e9lulas del c\u00e1ncer de pr\u00f3stata.<span class=\"citation\">2<\/span> La terapia hormonal se consolid\u00f3 como tratamiento fundamental del c\u00e1ncer de pr\u00f3stata despu\u00e9s de que Huggins y Hodges demostraran, en la d\u00e9cada de 1940, el efecto terap\u00e9utico de la privaci\u00f3n de testosterona gonadal, lo que estableci\u00f3 firmemente el c\u00e1ncer de pr\u00f3stata como una enfermedad altamente dependiente de los andr\u00f3genos.<span class=\"citation\">3<\/span> Aunque la terapia hormonal puede hacer que los c\u00e1nceres de pr\u00f3stata se reduzcan o crezcan m\u00e1s lentamente durante un tiempo, por s\u00ed sola no cura el c\u00e1ncer de pr\u00f3stata, y muchos c\u00e1nceres acaban haci\u00e9ndose resistentes a la terapia hormonal.<span class=\"citation\">1<\/span>\n    <\/p>","gt-synonyms":"Terapia de privaci\u00f3n de andr\u00f3genos (ADT), terapia de supresi\u00f3n androg\u00e9nica, castraci\u00f3n m\u00e9dica, castraci\u00f3n qu\u00edmica, terapia hormonal, terapia de bloqueo de andr\u00f3genos, bloqueo androg\u00e9nico combinado, bloqueo androg\u00e9nico completo, bloqueo androg\u00e9nico m\u00e1ximo, bloqueo androg\u00e9nico total","gt-citation":"[1] American Cancer Society. Hormone Therapy for Prostate Cancer. https:\/\/www.cancer.org\/cancer\/types\/prostate-cancer\/treating\/hormone-therapy.html\n\n[2] National Cancer Institute. Hormone Therapy for Prostate Cancer Fact Sheet. https:\/\/www.cancer.gov\/types\/prostate\/prostate-hormone-therapy-fact-sheet.\n\n[3] Desai K, McManus JM, Sharifi N. Hormonal Therapy for Prostate Cancer. Endocr Rev. 2021 May 25;42(3):354-373. DOI: 10.1210\/endrev\/bnab002. PMID: 33480983\n\n[4] Schaeffer EM, Srinivas S, Adra N, et al. Prostate Cancer, Version 4.2023, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023 Oct;21(10):1067-1096. DOI: 10.6004\/jnccn.2023.0050. PMID: 37856213","gt-clinical-context":"<p>\n        La terapia hormonal est\u00e1 cl\u00ednicamente indicada en varios escenarios del manejo del c\u00e1ncer de pr\u00f3stata.<span class=\"citation\">1<\/span> Puede utilizarse junto con la radioterapia como primer tratamiento del c\u00e1ncer que todav\u00eda se encuentra en la pr\u00f3stata o a su alrededor y que tiene un mayor riesgo de recurrencia.<span class=\"citation\">1,4<\/span> Tambi\u00e9n puede administrarse antes de la radioterapia para reducir el tama\u00f1o del c\u00e1ncer y hacer que el tratamiento sea m\u00e1s eficaz.<span class=\"citation\">1<\/span> En los pacientes cuyo c\u00e1ncer persiste o reaparece tras el tratamiento con cirug\u00eda o radioterapia, a menudo se recomienda la terapia hormonal, sobre todo si el c\u00e1ncer se ha diseminado.<span class=\"citation\">1,3<\/span> Adem\u00e1s, la terapia hormonal es el tratamiento de referencia cuando el c\u00e1ncer de pr\u00f3stata ha metastatizado demasiado como para curarse con cirug\u00eda o radioterapia.<span class=\"citation\">1,4<\/span>\n    <\/p>\n    <p>\n        Los criterios de selecci\u00f3n de pacientes incluyen a aquellos con enfermedad localizada de alto riesgo, recidiva bioqu\u00edmica tras el tratamiento primario y enfermedad metast\u00e1sica.<span class=\"citation\">3,4<\/span> El enfoque terap\u00e9utico var\u00eda en funci\u00f3n del estadio de la enfermedad, y se utilizan distintas combinaciones de f\u00e1rmacos hormonales en el c\u00e1ncer de pr\u00f3stata hormonosensible frente al resistente a la castraci\u00f3n.<span class=\"citation\">2,3<\/span> Los resultados esperados incluyen el control de la enfermedad y una supervivencia prolongada, aunque los efectos secundarios deben manejarse con cuidado.<span class=\"citation\">1,3<\/span> Avances cl\u00ednicos recientes han demostrado que la combinaci\u00f3n de la terapia hormonal con otros tratamientos, como la quimioterapia o los f\u00e1rmacos hormonales de segunda generaci\u00f3n, puede mejorar significativamente la supervivencia en el c\u00e1ncer de pr\u00f3stata metast\u00e1sico hormonosensible.<span class=\"citation\">3,4<\/span>\n    <\/p>","gt-related-evidence":null,"gt-featured":true,"gt-ai-referenced":false,"gt-view-count":104},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.7 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Terapia Hormonal for Prostate Cancer: ADT Treatment Guide<\/title>\n<meta name=\"description\" content=\"La terapia hormonal en urolog\u00eda reduce los niveles de andr\u00f3genos para frenar la progresi\u00f3n del c\u00e1ncer de pr\u00f3stata y controlar sus s\u00edntomas eficazmente.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.rigicon.com\/es\/glossary-term\/terapia-hormonal\/\" \/>\n<meta property=\"og:locale\" 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