{"id":12055,"date":"2025-07-17T03:31:33","date_gmt":"2025-07-17T07:31:33","guid":{"rendered":"https:\/\/www.rigicon.com\/glossary-term\/bladder-instillation\/"},"modified":"2026-10-06T18:04:24","modified_gmt":"2026-10-06T22:04:24","slug":"instilacion-vesical","status":"publish","type":"glossary-term","link":"https:\/\/www.rigicon.com\/es\/glossary-term\/instilacion-vesical\/","title":{"rendered":"Instilaci\u00f3n Vesical"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":0,"template":"","glossary-category":[],"glossary-product":[108,107],"class_list":["post-12055","glossary-term","type-glossary-term","status-publish","hentry","glossary-product-conticlassic-aus","glossary-product-contireflex-enhanced-aus"],"acf":{"gt-definition":"<p>La instilaci\u00f3n vesical es un procedimiento terap\u00e9utico que consiste en introducir un medicamento directamente en la vejiga a trav\u00e9s de una sonda y dejar que la soluci\u00f3n permanezca en ella durante un tiempo determinado antes de drenarla.<sup>1<\/sup> Este tratamiento administra el medicamento directamente en el revestimiento vesical, evitando la circulaci\u00f3n sist\u00e9mica y actuando sobre el tejido afectado.<sup>2<\/sup> El procedimiento se utiliza principalmente para tratar diversas afecciones vesicales, reparando la barrera urotelial da\u00f1ada, reduciendo la inflamaci\u00f3n y aliviando s\u00edntomas como el dolor, la urgencia y la polaquiuria.<sup>3<\/sup><\/p>\n    \n    <p>Una vejiga sana tiene una barrera protectora natural denominada capa de glucosaminoglucanos (GAG), que protege el revestimiento vesical de los irritantes presentes en la orina.<sup>4<\/sup> Cuando esta capa est\u00e1 da\u00f1ada, la orina puede entrar en contacto directo con el revestimiento vesical y causar inflamaci\u00f3n y s\u00edntomas. La instilaci\u00f3n vesical act\u00faa reduciendo la inflamaci\u00f3n y las molestias en la vejiga, lo que ayuda a aliviar estos s\u00edntomas y, posiblemente, a restaurar el revestimiento protector.<sup>5<\/sup><\/p>","gt-synonyms":"Lavado de vejiga, ba\u00f1o de vejiga, terapia intravesical, tratamiento intravesical, instilaci\u00f3n intravesical, instilaci\u00f3n vesical","gt-citation":"[1] Digesu GA, Tailor V, Bhide AA, Khullar V. The role of bladder instillation in the treatment of bladder pain syndrome: Is intravesical treatment an effective option for patients with bladder pain as well as LUTS? Int Urogynecol J. 2020 May;31(7):1387-1392. DOI: 10.1007\/s00192-020-04303-7\n\n[2] University Hospital Southampton NHS Foundation Trust. Bladder instillation - patient information. 2019. https:\/\/www.uhs.nhs.uk\/Media\/UHS-website-2019\/Patientinformation\/Womenshealth\/Bladder-instillation-1334-PIL.pdf\n\n[3] UC Irvine Department of Urology. Bladder Instillations. 2023. https:\/\/uciurology.com\/general-urology\/bladder-instillations\/\n\n[4] Interstitial Cystitis Association. Bladder Instillations. 2022. https:\/\/www.ichelp.org\/understanding-ic\/medical-treatments\/bladder-instillations\/\n\n[5] Hanno PM, Erickson D, Moldwin R, Faraday MM. Diagnosis and treatment of interstitial cystitis\/bladder pain syndrome: AUA guideline amendment. J Urol. 2015;193(5):1545-1553. DOI: 10.1016\/j.juro.2015.01.086","gt-clinical-context":"<p>La instilaci\u00f3n vesical est\u00e1 cl\u00ednicamente indicada en varias afecciones, como la cistitis intersticial\/s\u00edndrome de dolor vesical (CI\/SDV), las infecciones urinarias recurrentes, la acumulaci\u00f3n de sedimento en la orina, las sondas obstruidas y la capacidad vesical limitada que causa micciones frecuentes.<sup>1,3<\/sup><\/p>\n\n    <p>Las gu\u00edas cl\u00ednicas de la American Urological Association recomiendan las instilaciones vesicales como opci\u00f3n de tratamiento cuando los enfoques m\u00e1s conservadores, como la modificaci\u00f3n de la dieta, el control del estr\u00e9s y los productos de venta sin receta, no son suficientes para controlar los s\u00edntomas.<sup>4,5<\/sup><\/p>\n\n    <h3>Los criterios de selecci\u00f3n de pacientes suelen incluir a personas con:<\/h3>\n    <ul>\n        <li>Afecciones inflamatorias cr\u00f3nicas de la vejiga, como la cistitis intersticial<\/li>\n        <li>Vejiga dolorosa o s\u00edntomas de tipo cistitis<\/li>\n        <li>Polaquiuria y urgencia urinaria que no han respondido a los medicamentos orales<\/li>\n        <li>Infecciones urinarias recurrentes<\/li>\n        <li>Revestimiento vesical (capa de GAG) da\u00f1ado<sup>3,4<\/sup><\/li>\n    <\/ul>\n\n    <h3>El procedimiento consiste en:<\/h3>\n    <ol>\n        <li>Medir previamente la soluci\u00f3n del medicamento<\/li>\n        <li>Introducir una sonda a trav\u00e9s de la uretra hasta la vejiga<\/li>\n        <li>Instilar la soluci\u00f3n en la vejiga<\/li>\n        <li>Dejar que la soluci\u00f3n permanezca en la vejiga durante aproximadamente 15 minutos (el tiempo var\u00eda seg\u00fan el medicamento)<\/li>\n        <li>Drenar la soluci\u00f3n a trav\u00e9s de la sonda<sup>1,3<\/sup><\/li>\n    <\/ol>\n\n    <p>Los protocolos de tratamiento suelen consistir en instilaciones semanales durante 6-8 semanas, seguidas de tratamientos de mantenimiento cada pocas semanas o meses en funci\u00f3n de la respuesta de los s\u00edntomas.<sup>3,5<\/sup> Pueden utilizarse varios tipos de soluciones, entre ellas:<\/p>\n\n    <ul>\n        <li><strong>Dimetilsulf\u00f3xido (DMSO, nombre comercial RIMSO-50):<\/strong> La \u00fanica instilaci\u00f3n vesical aprobada por la FDA espec\u00edficamente para la CI\/SDV, aprobada en 1978. Act\u00faa reduciendo la irritaci\u00f3n vesical, relajando los m\u00fasculos de la vejiga y de la pelvis, aliviando el dolor al reducir los niveles de sustancia P y aumentando la capacidad vesical al prevenir la formaci\u00f3n de tejido cicatricial.<sup>4<\/sup><\/li>\n        <li><strong>Heparina:<\/strong> Ayuda a reparar el da\u00f1o del revestimiento mucoso de la vejiga y puede reducir las tasas de reca\u00edda de la CI.<sup>3<\/sup><\/li>\n        <li><strong>Hialuronato s\u00f3dico (Hyacyst):<\/strong> Contiene hialuronato s\u00f3dico, que ayuda a restaurar la capa de GAG.<sup>4<\/sup><\/li>\n        <li><strong>Mezclas\/c\u00f3cteles de rescate:<\/strong> Combinaciones de medicamentos como heparina, lignoca\u00edna (lidoca\u00edna) y bicarbonato s\u00f3dico.<sup>2,4<\/sup><\/li>\n    <\/ul>\n\n    <p>Los resultados esperados incluyen la mejor\u00eda de los s\u00edntomas en un plazo de 3-4 semanas tras el inicio del tratamiento, con la posibilidad de controlar a largo plazo las afecciones cr\u00f3nicas mediante tratamientos de mantenimiento.<sup>3<\/sup><\/p>","gt-related-evidence":null,"gt-featured":true,"gt-ai-referenced":false,"gt-view-count":172},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.7 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Instilaci\u00f3n Vesical<\/title>\n<meta name=\"description\" content=\"La instilaci\u00f3n vesical administra medicamentos directamente en la vejiga mediante una sonda para tratar la cistitis intersticial y otras patolog\u00edas.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.rigicon.com\/es\/glossary-term\/instilacion-vesical\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Instilaci\u00f3n Vesical - Prosthetic Urology 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